2007 - Ubiquitin and Cancer

Alan D’Andrea - The Fanconi Anemia Pathway and the DNA Damage Response

Peter Jackson - Protein Destruction in Mitosis: Cyclins, Spindles and Chromosome Segregation

Zhijian (James) Chen - Ubiquitin-Mediated Activation of NF-kappaB and its Role in Cancer

William Kaelin - The von Hippel-Lindau Tumor Suppressor Protein: Oxygen Sensing and Cancer

2006 - Stem Cells in Cancer and Development

2005 - Cellular Responses to DNA Damage and Cancer

Thomas Kunkel, Ph.D. - DNA Replication (IN) Fidelity-Causes and Consequences

Jean Wang, Ph.D. - Coordination of DNA Repair and Cell Death Response

Wei Yang, Ph.D. - Making and Breaking DNA: Lessons From Structural Studies

Jan Hoeijmakers, Ph.D. - DNA Damage and Repair: At the Crossroads of Cancer and Aging

2004 - Metastasis: Biology and Therapeutic Strategies

Lynn Matrisian, Ph.D. - What We’ve Learned from the matrix Metalloproteinase Inhibitor Clinical Trials

Danny Welch, Ph.D. - Metastasis Controlling Genes

Ruth Muschel, M.D., Ph.D. - Mechanisms of Metastasis

Patricia Steeg, Ph.D. - Translational Leads in Breast Cancer Metastasis

2003 - Cell Biology of Breast Cancer

Jeffrey T. Holt, M.D. - Pathobiology and Genetics of Breast Cancer

Nita Maihle, Ph.D. - Growth Factor Regulation of Breast Cancer

William Muller, Ph.D. - Transgenic Models of Breast Cancer

Nora Disis, M.D. - Novel Therapeutics for the Treatment of Breast Cancer

2002 - Cancer Genetics

Gerard I. Evan, Ph.D. - Genetic control of apoptosis, cancer, oncogenes

Donna G. Albertson, Ph.D. - Breast cancer genetics, genome scanning with comparative genomic hybridization

William G. Kaelin, M.D. - Tumor suppressor genes, p53, von Hippel-Lindau, genetic-based therapies

William P. Bennett, M.D. - Genetic susceptibility to lung cancer, genetic epidemiology

2001 - Tumor Immunology

Matthew Mescher, Ph.D. - T Lymphocyte Responses to Tumors

James Mulé, Ph.D. - Tumor Vaccines

Jeffrey Weber, M.D., Ph.D. - Clinical Immunotherapy Trials

Ellen Vitetta, Ph.D. - Monoclonal Antibody Therapies For Cancer

2000 - Angiogenesis

Robert Kerbel, Ph.D. - Tumor Angiogenesis: Underlying Principles and Potential as a Therapeutic Target

Rakesh Jain, Ph.D - Tumor Angiogenesis and Microcirculation: Lessons From In Vivo Microscopy of Gene Expression and Function

Renata Pasqualini, Ph.D - Molecular Anatomy of Blood Vessels

David Shalinsky, Ph.D. - Matrix Metalloprotease (MMPs) in Neoplastic Progression: Therapeutic Strategies Aimed at Inhibiting Angiogenesis, Invasion and Metastasis Using MMP Inhibitors

1999 - Telomeres

Jerry W. Shay, Ph.D. - Aging & Cancer: Are Telomeres and Telomerase the Connection?

Lea Harrington, Ph.D. - Form & Function of Mammalian Telomerase

Peter Lansdorp, MD, Ph.D. - Telomeres & Chromosomal Stability in Mammalian Cells

Julia Promisel Cooper, Ph.D. - Telomere Function During Mitosis and Meiosis in Fission Yeast

1998 - Chromatin Structure and Gene Expression

C. David Allis, Ph.D. - Linking Histone Acetylation and Phosphorylation to Gene Activation

Craig Peterson, Ph.D. - Transcriptional Regulation by Chromatin Remodeling Machines

Marc Montminy, M.D., Ph.D. - CBP and p300: General Mediators of Cell Signaling

Michelle Barton, Ph.D. - In Vitro Reconstitution of Gene Regulation Using Chromatin Structure and Synthetic Nuclei Templates

1997 - Apoptosis: Molecular Mechanisms and Clinical Implications

Stan Korsmeyer, M.D. - BCL-2 Family and the Regulation of Cell Death

Michael Hengartner, Ph.D. - Apoptosis and Development

Junying Yuan, Ph.D. - Control of Apoptosis by the Caspase Family

David Fisher, M.D. - Apoptosis in Tumorigenesis and Cancer Therapy
 

1996 - Characterization and Therapy of Genetic Disorders

Jim Sikela, Ph.D. - Progress Toward a Human Gene Map

Webster Cavenee, Ph.D. - Genetics of Tumor Progression

John Engelhardt, Ph.D. - Vectors for Gene Therapy of Inherited and Acquired Diseases

Stephen Eck, M.D., Ph.D. - Laboratory and Clinical Approaches to Cancer Gene Therapy

1995 - Genetics of Development

Paul W. Sternberg, Ph.D. - Intercellular Signaling and Signal Transduction During C. Elegans Development

Utpal Banerjee, Ph.D. - Signal Transduction and Neuronal Development in the Drosophila Eye

Michael S. Levine, Ph.D. - Transcriptional Control of Drosophila Embryogenesis

Mario R. Capecchi, Ph.D. - The Role of Hox Genes in Establishing the Mammalian Body Plan

1994 - Transcription factors as Effectors of Signal Transduction

Nancy H. Colburn, Ph.D. - Induced AP-1 as a Possible Target for Prevention of Carcinogenesis

Gail Sonenshein, Ph.D. - Regulation of c-myc Expression and the Role of NF-kB Rel-related Family of Factors

Lorraine Gudas, Ph.D. - Retinoids: Signalling Molecules for Cell Growth and Differentiation

Frank Rauscher, III, Ph.D. - Transcription Factors as Negative Regulators of Cell Growth: Studies on WT-1 and P53

1993 - Cell Cycle Regulation

Leland H. Hartwell, Ph.D. - Mitotic Instability and Cancer

Andrew Murray, Ph.D. - Mitotic Feedback Controls: How Cells Know When to Leave Mitosis

Patrick O'Farrell, Ph.D. - Formation of Embryonic Pattern and the Developmental Controls of Cell Proliferation

Thea Tltsy, Ph.D. - The Genetic Regulation of Genomic Instability in Normal and Neoplastic Cells

1992 - DNA Replication, DNA Repair and Mutagenesis

Lawrence A. Loeb, M.D., Ph.D. - Endogenous Mutagenesis and Cancer

Thomas Kunkel, Ph.D. - Studies of the Fidelity of Eukaryotic DNA Replication

Michael Cox, Ph.D. - Recombinational DNA Repair Mediated by the RecA System

Philip Hanawalt, Ph.D. - Intragenomic Fine Structure of DNA Repair

1991 - Tumor Suppressor Genes and Transcription Regulatory Factors

Edward Harlow, Ph.D. - Proteins that are Cellular Targets for Transformation of DNA Tumor Viruses

W. Edward Mercer, Ph.D. - Tumor Suppressor Genes and Transcription Regulatory Factors

Edward Ziff, Ph.D. - Gene Regulation by Growth Factors

Steven Friend, M.D., Ph.D. - Germ Line Tumor Suppressor Genes - Risks for Cancer