Oksana Lockridge, (Recent Selected Publications)


Peeples ES, Schopfer LM, Duysen EG, Spaulding R, Voelker T, Thompson CM, Lockridge O (2005) Albumin, a new biomarker of organophosphorus toxicant exposure, identified by mass spectroscopy.  Tox Sci 83: 303-312

Lockridge O, Duysen EG, Voelker T, Thompson CM, Schopfer LM (2005) Life without acetylcholinesterase:  the implications of cholinesterase inhibitor toxicity in AChE-knockout mice.  Environmental Toxicology and Pharmacology 19: 463-469.

Schopfer LM, Voelker T, Bartels CF, Thompson CM, Lockridge O (2005) Reaction kinetics of biotinylated organophosphorus toxicant,  FP-biotin, with human acetylcholinesterase and human butyrylcholinesterase.  Chem Res Toxicol 18: 747-754.

Lockridge O, Schopfer LM, Winger G, Woods JH (2005)  Large scale purification of butyrylcholinesterase from human plasma suitable for injection into monkeys;  a potential new therapeutic for protection against cocaine and nerve agent toxicity.   J Medical Chemical  Biological & Radiological Defense Volume 3, published online 1 Jul 2005.

Schopfer LM, Champion MM, Tamblyn N, Thompson CM, Lockridge O (2005) Characteristic Mass Spectral Fragments of the Organophosphorus Agent FP-biotin and FP‑biotinylated Peptides from Trypsin and Bovine Albumin (Tyr410). Anal Biochem 345: 122-132.

Li B, Sedlacek M, Manoharan I, Boopathy R, Duysen EG, Masson P, Lockridge O (2005)  Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase,  are present in human plasma.  Biochem Pharmacol 70: 1673-1684.

Lockridge O, Schopfer LM (2006)  Biomarkers of organophosphate exposure.  Chapter 48 in Toxicology of Organophosphate and Carbamate Compounds. Edited by Ramesh C. Gupta.  Elsevier Academic Press, Amsterdam. pp 703-711.