Xu Luo, Ph.D. (Selected Publications)


Luo, X. and Sawadogo, M. (1996). Antiproliferative properties of the USF family of helix-loop-helix transcription factors. Proc. Natl. Acad. Sci. U.S.A. 93, 1308-1313.

Luo, X. and Sawadogo, M. (1996). Functional domains of transcription factor USF2: Atypical nuclear localization signals and context-dependent transcriptional activation domains. Mol. Cell. Biol. 16, 1367-1375.

Liu, X., Li, P., Widlak, P., Zou, H., Luo, X., Garrad, W., and Wang, X. (1998). DFF40 induces chromatin DNA fragmentation and condensation during apoptosis. Proc. Natl. Acad. Sci. U.S. A. 95, 8461-8466.

Luo, X., Budiharjo, I., Zou, H., Slaughter, C., and Wang, X. (1998). Bid, a Bcl-2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94, 481-490.

Qyang,Y., Luo, X., Lu, T., Ismail, P.M., Krylov, D., Vinson, C., and Sawadogo, M. (1999). Cell-type-dependent activity of the ubiquitous transcription factor USF in cellular proliferation and transcriptional activation. Mol. Cell. Biol. 19, 1508-1517.

Sawadogo, M., Luo, X., Sirito, M., Lu, T., Ismail, P.M., Qyang, Y., and Szentirmay, M.N. (1999). Biological function of the USF family of transcription factors. Gene Ther. Mol. Biol. 3, 447-453.

Budiharjo, I., Oliver, H., Lutter, M., Luo, X., and Wang, X. (1999). Biochemical pathways of caspase activation during apoptosis. Annu. Rev. Cell Dev. Biol. 15, 269-290.

Lutter, M., Fang, M., Luo, X., Nishijima, M., Xie, X., Wang, X. (2000). Cardiolipin provides specificity for targeting of tBid to mitochondria. Nat. Cell Biol. 10, 754-761.

Li, L., Luo, X., and Wang, X. (2001). Endonuclease G is an apoptotic DNase when released from mitochondria. Nature 412, 95-99.

Basma, H, El-Refaey, H, Sgagias MK, Cowan KH, Luo, X., Cheng PW. (2005). BCL-2 antisense and cisplatin combination treatment of MCF-7 breast cancer cells with or without functional p53. J Biomed Sci. 12, 999-1011.

Huang, Y., Erdmann, N., Peng, H., Herek, S., Davis, J., X. Luo, Ikezu, T., and Zheng, J. (2006). TRAIL-Mediated Apoptosis in HIV-1-Infected Macrophages Is Dependent on the Inhibition of Akt-1 Phosphorylation. J Immunol. 177, 2304-2313.

George, N. M., Evans, J.D., and Luo, X. (2007). A Three Helix Homo-oligomerization Domain Containing BH3 and BH1 is Responsible for the Apoptotic Activity of Bax. Genes Dev. 21, 1937-1948.