Yutong Liu,
Uberti MG, Dou H, Banerjee R, Grotepas CB, Stone DK, Rabinow BE, Gendelman
HE, Boska MD, Ingress of blood-borne macrophages across the blood-brain
barrier in murine HIV-1 encephalitis. J Neuroimmunol, 2008 Aug
30;200(1-2):41-52.
Yutong Liu,
H. D'Arceuil, J. He, M. Duggan, G. Gonzalez, J. Pryor, A. de Crespigny, MRI
of spontaneous fluctuations after acute cerebral ischemia in nonhuman
primates, J Magn Reson Imaging, 2007 Oct;26(4):1112-6.
Yutong Liu,
H. D'Arceuil, S. Westmoreland, J. He, M. Duggan, G. Gonzalez, J. Pryor, A.
de Crespigny, Serial diffusion tensor magnetic resonance imaging (MRI) after
transient and permanent cerebral ischemia in nonhuman primates, Stroke,
38(1): 138-145, Jan. 2007
Yutong Liu,
H . D'Arceuil, J. He, M. Duggan, G. Gonzalez, J. Pryor, A. de Crespigny, A
nonlinear mesh-warping technique for correcting brain deformation after
stroke. Magn Reson Imaging. 2006 Oct; 24(8):1069-75.
Yutong Liu,
D'Arceuil H, He J, Duggan M, Seri S, Hashiguchi Y, Nakatani A, Gonzalez RG,
Pryor J, de Crespigny A., Dynamic susceptibility contrast perfusion imaging
of cerebral ischemia in nonhuman primates: comparison of Gd-DTPA and NMS60,
J Magn Reson Imaging., 22(4):461-6, Oct . 2005
Yutong Liu,
K. Pekkan, C. Jones, and A. P. Yoganathan, The effects of different mesh
generation methods on computational fluid dynamic analysis and power loss
assessment in total cavopulmonary connection, J Biomech Eng, 126(5):594-603.
Oct. 2004.
Yutong Liu, A. Hamilton, A.
Nagaraj, L. Yan, K. Liu, Y. Lai, D. D. McPherson, K. B. Chandran,
Alteration in fluid mechanics in porcine femoral arteries with atheroma
development, Ann Biomed Eng, 32(4):544-54, Apr. 2004
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MAJOR EQUIPMENT: The Bruker Biospec 7T/21cm MRI/MRS system with a full range
of options is installed in our laboratory. The system operates on a Linux
workstation and includes a full range of imaging and spectroscopy pulse
sequences and associated analysis programs. The 2-channel RF system
includes a 400W pulse power RF amplifier for the proton channel (300 MHz)
and a broadband 1 Kw X-nucleus channel. The system includes actively
decoupled proton transmit coil (7 cm ID) and a reception surface coils (two)
optimized for rat and mouse brain studies, respectively. Also included are
3 proton RF coils for imaging studies using the high performance gradient
insert (15 mm, 25 mm and 35 mm ID), an 8-channel physiological monitoring
system (Bruker) integrated with the scanner to allow for gating and motion
correction of images. In addition, we have developed a suite of laboratory
built animal holders and coils. The Bruker Pharmascan system (7T/16 cm)
includes a 2 channel actively decoupled volume transmit coil/surface coil
system, physiological monitoring system, and upgraded gradients and shim and
actively shielded gradient system, and the Bruker spectroscopy and diffusion
tensor imaging (DTI) packages. This will allow pertinent developments in
mouse brain spectroscopic imaging and DTI to be directly applied to the new
scanner.
Laboratory: Two adjacent 600 s.f. laboratories (rm UH1324 and 1327) house
two Bruker animal MRI/MRSI systems. Both laboratories have anesthesia
equipment and animal preparation areas. Both laboratories have access to
medical gasses for the anesthesia apparatus, an exhaust system for
anesthetic gasses. An adjacent 630 s.f. room is subdivided into three areas
and used for a probe development laboratory (UH1330A), chemical preparation
laboratory (UH1330B) and data processing laboratory (1017 & 1021 ESH).
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