National
Institutes of Health, Volume Reflex in Diabetic Rats, 04-01-94/03-31-99,
Principal Investigator.
American
Heart Association, Noradrenergic Influences on Renal Function in Heart
Failure, 07-01-96/06-30-99, Principal Investigator.
American
Diabetes Association, Volume Regulation in Diabetes: Intrarenal Mechanisms,
07-01-98/06-30-00, Principal Investigator.
National
Institutes of Health, Volume Regulation in Diabetes: Intrarenal Mechanisms, 05/01/99
to 04/30/04, Principal Investigator.
PPG
Grant, Project II, National Institutes of Health, Function of the PVN in Heart
Failure: Role of NO and GABA, 04-01-99/03-31-04, Principal Investigator.
National
Institutes of Health, Altered nitric oxide mechanisms in the PVn during
diabetes, 05-01-99/04-30-04, Principal Investigator.
National
Institutes of Health, Cardiopulmonary Reflexes in Heart Failure,
07-01-87/06-30-02, Co-Investigator.
Juvenile
Diabetes Foundation International, Renal Microvascular Angiotensin II/Nitric
Oxide Interactions in Diabetes Mellitus, Co-Investigator.
American
Heart Association, NE Affiliate, Endothelin and Sympathetic Nerve Activity in
Heart Failure, 07-01-99/06-30-99, Co-Investigator.
National
Institutes of Health, Cardiovascular Research Training Program,
07-01-98/06-30-02, Co-Investigator.
National
Institutes of Health, Cerebral Microcirculation During Alcohol Consumption,
01-01-99/12-31-03, Co-Investigator.
National
Institutes of Health, Heart Failure and Sympathetic Outflow,
04-01-99/03-31-04, Co-Investigator.
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Rozanski, G.J., Z. Xu, K. Zhang and K.P. Patel. Altered
ionic currents of ventricular nucleus mediates changes in renal sympathetic
nerve activity. Am. J. Physiol. 274:H259-H265, 1998.
Patel, K.P. Neural regulation in experimental heart
failure. In: Neurocardiology, Ed. D. Cechetto and V. Hachinski, W.B. Saunders,
London, pp. 283-296, 1998.
Zhang, K., I.H. Zucker and K.P. Patel. Altered number of
diaphorase (NOS) positive neurons in hypothalamus of rats with heart failure.
Brain Res. 786:219-225, 1998.
Mayhan, W.G. and K.P. Patel. Treatment with
dimethylthiourea prevents impaired dilation of the basilar artery during
diabetes mellitus. Am.J. Physiol. 274:H1895-H1901, 1998.
Zhang, K., K.P. Patel. Effect of nitric oxide within the
paraventricular nucleus on renal sympathetic nerve discharge: Role of GABA.
Am. J. Physiol. 275:R728-R734, 1998.
Ikenage, H., S.P. Didion, K. Zhang, K.G. Cornish, N. Ishii,
K.P. Patel, W.G. Mayhan and P.K. Carmines. Suppressed impact of nitric oxide
on renal arteriolar function in rats with chronic heart failure. Am. J.
Physiol. 276:F79-F87, 1999.
Patel, K.P. Role of paraventricular nucleus in mediating
sympathetic outflow in heart failure. Heart Failure Reviews, 2000.
Patel, K.P., K. Zhang, P.K. Carmines. Turnover of
norepinephrine in peripheral tissues of rats with heart failure. Am. J.
Physiol. Reg. Physiol. 2000.
McConnell, P.I., C.E. Olson, K.P. Patel, D.U. Blank, M.T.
Olivari, K.P. Gallagher, E. Quenby-Brown, I.H. Zucker. Chronic endothelin
blockade in dogs with pacing-induced heart failure: Possible modulation of
sympatho-excitation. J. Cardiac Failure 6(1):56-65, 2000.
Fitch, G.K., K.P. Patel, M.L. Weiss. Activation of renal
afferent pathways following furosemide treatment: Effect of survival time and
renal denervation. Brain Res., in press, 2000.
Liu, J.-L., S. Irvine, I.A. Reid, K.P. Patel, I.H. Zucker.
Chronic exercise reduces sympathetic nerve activity in rabbits with
pacing-induced heart failure. Circulation 102:1854-1862, 2000.
Shontz R.D., Xu Z., PATEL,
K.P. and Rozanski, G.J. Inhibition of K+ currents by homocysteine in rat
ventricular myocytes. J. Cardiac Electrophysiology 12:175-182, 2001.
PATEL, K.P.
and Carmines, P.K. Renal
interstitial hydrostatic pressure and sodium excretion during acute volume
expansion in diabetic rats. Am. J. Physiol. 281:R239-R245, 2001.
Ishii, N, PATEL, K.P., Lane,
P.H., Taylor, T., Bian, K. Murad, F. Pollock, J.S., and Carmines P.K. Nitric
oxide synthesis and degradation in the renal cortex of rats with diabetes
mellitus. J. Am. Soc. Neph. 12:1630-1639, 2001.
Zucker, I.H., Wang, W., Pliquett, R.U., Jun-Li, L., Irvine, S., and
PATEL, K.P.
The regulation of sympathetic outflow in heart failure: The role of
Angiotensin II, Nitric oxide and Exercise training.
Ann. New York Academy Sci. 940:431-443, 2001.
Zhang, K., Li, Yi-Fan and PATEL,
K.P. Blunted nitric
oxide-mediated inhibition of renal nerve discharge within the paraventricular
nucleus of rats with heart failure. Am. J. Physiol. 281:H995-H1004, 2001.
PATEL, K.P., Yi-Fan Li and Y. Hirooka. The role of nitric oxide on
central sympathetic outflow. Proc. Soc. Exp. Bio. Med. 226(9):814-824, 2001.
(Invited review)
Kenney, M.J., Weiss, M.L., PATEL, K.P., Wang, Yan and Fels, R.J.
Paraventricular nucleus bicuculline alters the frequency components of
sympathetic nerve discharge bursts. Am .J. Physiol. 281:H1233-H1241, 2001.
Sun, H, PATEL, K.P. and Mayhan, W.G. Tetrahydrobiopterin, a
cofactor for NOS, improves endothelial dysfunction during chronic alcohol
consumption Am. J. Physiol.
281:H1863 H1869, 2001.
Weiss, M.L., Chowdhury, S.I., PATEL, K.P., Kenney, M.J.,Huang, J.
Neural circuitry of the kidney; NO containing neurons. Brain Res. 919:269-282,
2001.
Li, Yi-Fan, Mayhan,W.G. and PATEL,
K.P. NMDA-mediated increase
in renal sympathetic nerve discharge within the PVN: Role of nitric oxide.
(Am. J. Physiol. In Press- 2001)
Xu Z., PATEL, K.P., Lou,
M.F. and Rozanski, G.J. Up-reulation of K+ channels in diabetic rat
ventricular myocytes by insulin and glutathione. (In Press - Cardiovas. Res.
2001)
Li, Yi-Fan, Roy, S.K., Channon, K., Zucker,I.H., and PATEL,
K.P. Effect of in-vivo gene transfer of neuronal nitric oxide
synthase (nNOS) in the PVN on renal nerve discharge in rats. (Am. J. Physiol.
- In Press- 2001)
Zhang, K., Li, Yi-Fan and PATEL, K.P.
Blunted GABA-mediated inhibition of renal nerve discharge within the
paraventricular nucleus of rats with heart failure. (Am. J. Physiol. In Press
- 2001)
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