Division of Radiation Science Technology Education
University of Nebraska Medical Center
984545 Nebraska Medical Center
Omaha, NE 68198-4545
Assistant Professor, 2013
B.Sc., Diagnostic Radiologic Technology, Kuwait University, Kuwait City, Kuwait, 1989
Ph.D., Free Radicals and Radiation Biology, University of Iowa, Iowa City, Iowa, USA, 2003
Primary Teaching Responsibilities:
RSTE 414R Health Physics
RSTE 438N Advanced Radiation Biology
RSTE 312R Radiologic Technology I
RSTE 313R Radiologic Technology II
RSTE 413R Radiographic Contrast Media
RSTE 305R Special Projects
Visiting Scientist: University of Cincinnati (July-Sept. 2005)
Working on the oxidative stress induced by pyocyanin in A549 and HBE cells.
The study includes the study of expression of Glutathione (total and mitochondrial), HO-1, Thioredoxin, and HIF-1alpha.
Visiting Scientist: University of Iowa (June-Aug. 2006)
Working on 2-deoxyglucose-induced sensitization to p53 induced cell death in prostate cancer cells.
Visiting Scientist: University of Iowa (June-Aug. 2007)
Working on radiation therapy, metabolic oxidative stress, and cancer biology project.
Visiting Scientist: University of Iowa (June-Aug. 2008)
Working on cancer therapy related projects that involve imaging responses to 2-deoxyglucose-induced radiosensitization and radiation-induced genomic instability.
Conduct research in ongoing redox biology studies using state-of-the art techniques to measure levels of antioxidants and oxidants in biological samples; involved in designing and optimizing experimental protocols; and writing collaborative research grants.
Publications (last 5 years):
Savalia K, Manickam DS, Rosenbaugh EG, Tian J, Ahmad IM, Kabanov AV, Zimmerman MC. Neuronal uptake of nanoformulated superoxide dismutase and attenuation of angiotensin II-dependent hypertension after central administration. Free Radical Biology and Medicine. 73 (2014) 299-307.
Abdalla MY, Mathahs MM, Ahmad IM. (2012) Reduced heme oxygenase-1 expression in steatotic livers infected with hepatitis C virus. European Journal of Internal Medicine 23(7): 649-655.
Abdalla MY, Mathahs MM, Ahmad IM. (2012) Protective Role of Heme Oxygenase-1 in Liver. Biologia. 67(4): 623-628.
Ahmad IM, Abdalla MY. (2012) Mitochondria-Mediated Oxidative Stress and Cancer Therapy. In: Spitz DR. et al. (eds.). Oxidative Stress in Cancer Biology and Therapy, Oxidative Stress in Applied Basic Research and Clinical Practice. Springer Science and Business Media, LLC; Part 1, pp 3-19.
Fath MA, Ahmad IM, Smith CJ, Spence J, Spitz DR. (2011) Enhancement of carboplatin-mediated lung cancer cell killing by simultaneous disruption of glutathione and thioredoxin metabolism. Clinical Cancer Research. 17(19):6206-17.
Abdalla MY, Fawzi M, Al-Maloul SR, El-Banna N, Tayyem RF, Ahmad IM. (2011) Increased Oxidative Stress and Iron Overload in Jordanian B Thalassemic Children. Hemoglobin. 35(1):67–79.
Ahmad IM, Britigan BE, Abdalla MY. (2011) Oxidation of thiols and modification of redox-sensitive signaling in human lung epithelial cells exposed to Pseudomonas pyocyanin. Journal of Toxicology and Environmental Health, Part A. 74:43-51.
Abdalla MY, Hassan IM, Mustafa NH, Tahtamouni LH, Ahmad IM. (2011) Total body glutathione depletion induces oxidative stress and disrupts the immune function in mice. Toxicological & Environmental Chemistry. 93(1): 157-170.
Ahmad IM, Mustafa EH, Mustafa NH, Tahtamouni LH, Abdalla MY. (2010) 2DG enhances the susceptibility of breast cancer cells to doxorubicin. Central European Journal of Biology. 5(6):739-748.
Abu- Surrah AS, Abu Safieh KA, Ahmad IM, Abdalla MY, Ayoub MT, Qaroush AK, Abu-Mahtheieh AM. (2010) New palladium(II) complexes bearing pyrazole-based Schiff base ligands: Synthesis, characterization and cytotoxicity. European Journal of Medicinal Chemistry. 45:471-475.
Ahmad IM, Mattson DM, Dayal D, Parsons AD, Aykin-Burns N, Li L, Orcutt KP, Spitz DR, Dornfeld KJ, Simons AL. (2009) Cisplatin combined with zidovudine enhances cytotoxicity and oxidative stress in human head and neck cancer cells via a thiol-dependent mechanism. Free Radical Biology & Medicine. 46(2):232-7.
Aykin-Burns N, Ahmad IM, Zhu Y, Oberley LW, Spitz DR. (2009) Increased levels of superoxide and H2O2 mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation. Biochemical Journal. 418:29-37.
Ahmad IM, Abdalla MY, Aykin-Burns N, Simons AL, Oberley LW, Domann FE and Spitz DR. (2008) 2-Deoxyglucose combined with wild type p53 over expression enhances cytotoxicity in human prostate cancer cells via oxidative stress. Free Radical Biology & Medicine.44: 826-834.
Publications In Progress:
Krupa K. Savalia, Devika S. Manickam, Erin G. Rosenbaugh, Jun Tian, Iman M. Ahmad, Alexander V. Kabanov, Matthew C. Zimmerman. (2013) NANOFORMULATED COPPER/ZINC SUPEROXIDE DISMUTASE: ALTERNATIVE PHARMACOTHERAPY FOR ANGIOTENSIN II-DEPENDENT NEUROGENIC HYPERTENSION. In progress.
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Iman M. Ahmad, PhD