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David Klinkebiel
Assistant Professor, Biochemistry and Molecular Biology
Ph.D., University of Nebraksa-Lincoln, 1990.
Phone: (402) 559-3842
Lab: (402) 559-9303
Fax: (402) 559-6650
Email: dklinkebiel@unmc.edu
Click here for further publications.
Influence of DNA methylation on gene expression and the association with cancer development.
RECENT PUBLICATIONS:
Yang, J.L., Klinkebiel, D., Boland, M.J., Tang, L., Christman, J.K., 2006. Promoter methylation and mRNA expression of APC gene in MCF10 breast cancer model. Chinese Journal of Pathology. Zhonghua Bing Li Xue Za Zhi. Jan;35(1):32-6. Abstract
Yang, J.L., Klinkebiel, D., Boland, M.J., Tang, L., Christman, J.K. 2007. Promoter methylation and mRNA expression of WT1 gene in MCF10 breast cancer model. Chinese Journal of Pathology. Zhonghua Bing Li Xue Za Zhi. Apr;36(4):253-8. Abstract
Radhakrishnan, P., Basma, H., Klinkebiel, D., Christman, J., Cheng, P.W. 2008 Cell type-specific activation of the cytomegalovirus promoter by dimethylsulfoxide and 5-Aza-2'-deoxycytidine. Int. J. Biochem. Cell Biol. 40(9)1944-55. Epub Mar 7 2008. Abstract
Chew YC, West JT, Kratzer SJ, Ilvarsonn AM, Eissenberg JC, Dave BJ, Klinkebiel D, Christman JK, Zempleni J. Biotinylation of histones represses transposable elements in human and mouse cells and cell lines and in Drosophila melanogaster. J Nutr. 138(12):2316-22, 2008. Abstract
Iqbal J, Kucuk C, Deleeuw RJ, Srivastava G, Tam W, Geng H, Klinkebiel D, Christman JK, Patel K, Cao K, Shen L, Dybkaer K, Tsui IF, Ali H, Shimizu N, Au WY, Lam WL, Chan WC. Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies. Leukemia 2009 Feb 5. [Epub ahead of print] Abstract
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