Cancer Biology

Cancer Biology Faculty List

Cancer Biology imageDespite impressive progress during the past 30 years, cancer remains one of the most complex and challenging problems of biomedical research. For this reason, cancer research is a key component of the Biomedical Research Training Program. Cancer researchers at UNMC are engaged in work that addresses the root causes of cancer, as well as the means of enhancing the detection and treatment of cancer. This research employs a wide range of animal and cellular model systems, includes both basic and translational research, and focuses heavily on the molecular basis of cancer.

Research Programs

Areas of particular strength include focus groups working on cancers of the prostate, breast, pancreas and blood. Cancer research at UNMC is recognized and supported by the National Cancer Institute.

Causes of Cancer: This area of research includes evaluation of the genetic, environmental and nutritional factors that contribute to cancer incidence as well as cancer prevention. Some research approaches utilized in this area of inquiry include:

  • Functional Genomics
  • DNA damage and repair
  • Nutrition and cancer
  • Environmental risk factors
  • Cancer genetics
  • Animal models of cancer

Molecular and Cellular Ramifications of Cancer: This research is focused on the differences in molecules and cells that help define cancer at the microscopic level. The following avenues are taken in research at the molecular level:

  • Gene expression
  • Signal transduction
  • Structural biochemistry
  • Functional Genomics

Diagnostics and Therapeutics: State-of-the-art technology couples with cutting-edge cancer research at UNMC to identify new ways of diagnosing and treating cancer. Several research innovations are used, including:

  • Functional Genomics
  • Tumor vaccine development
  • Radioimmunoconjugate therapy
  • Gene-targeted therapy
  • B-cell and T-cell mediated therapies