Immunology

Immunology Faculty List

Immunology research at the UNMC is multifaceted with interests ranging from autoimmune and inflammatory diseases, oncology, hematology, and infectious diseases to neurologic dysfunction. Immunology has obvious significance in the biology of disease resistance, but also has important implications for developing modern therapies such as those involving organ transplants and stem cell transplantation. The field of immunology also plays a more central role in understanding psychological-biochemical responses of the body and the role of inflammatory responses in neurodegeneration.

Researchers and students with interests in immunology can keep in touch via several group meetings on immunology topics: the Immunology Interest Group, TransIn addition, there are three core facilities directly related to supporting immunology research: the Cell Analysis Facility, the Monoclonal Antibody Facility and the Molecular Diagnostic Laboratory.

Research Programs:

Stem cell transplantation and cytokines:

  • Cytokine effects on stem cell mobilization and bone resorption / formation
  • Stem cell mobilization and growth factor effects on immunologic reconstitution
  • Cytokines for adjuvant activity for vaccines
  • Cytokine therapy in autoimmune diseases such as diabetes

Immunology and disease:

  • Vaccine therapy for cancers
  • Host - tumor interactions
  • Mechanism of tumor-specific antigen presentation to T cells
  • Host-resistant mechanisms in infectious diseases
  • Alcohol effects on innate immunity
  • Acute phase proteins and their role in inflammatory processes

Neuro-immunologic interactions:

  • The role of inflammation in neurodegenerative diseases
  • microglial / macrophage modulation of neural activity
  • psychoneural regulation of the immune system
  • cytokine receptor function in the CNS

Virology:

  • Enterovirus biology
  • Autoimmune disease
  • Virus-receptor interactions
  • Viral vector technology
  • Mechanisms of HIV pathology

 

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