Molecular Biology Faculty

BRTP Faculty - Molecular Biology

Vimla Band, Professor and Chairperson, Genetics, Cell Biology and Anatomy; Ph.D., All India Institute of Medical Sciences, India, 1985.  Delineate molecular mechanisms of early steps in transformation of mammary epithelial cells with the goal of identifying novel molecular diagnostic/prognostic markers and potential therapy targets of breast cancers.

Surinder K. Batra, Professor Chairperson, Biochemistry and Molecular Biology, COM, Courtesy Associate Professor, Eppley Research Institute, Courtesy Associate Professor, Pathology/ Microbiology, COM; Ph.D., Kurukshetra University (India), 1983.  Structure/Function Analysis of Tumor-Associated Genes.

Kenneth W. Bayles, Professor, Pathology and Microbiology; Ph.D., Kansas State Univ., 1989.  Bacterial infections and antibiotic resistance.

Robert G. Bennett, Associate Professor, Internal Medicine - DEM; Ph.D., UNMC, 1998. Action and degradation of insulin/relaxin family hormones.

Tadayoshi Bessho, Associate Professor, Cancer Research Graduate Program; Ph.D., Okayama Univ., Japan 1991.  Molecular mechanism of DNA interstrand crosslink repair in mammalian cells.

Kishor Bhakat, Associate Professor, Genetics, Cell Biology and Anatomy; Ph.D., University of Calcutta, 1999. Mitotic gene bookmarking: A novel dimension of epigenetic memory in post-mitotic transcriptional reactivation.

Stephen Bonasera, Associate Professor, Internal Medicine - Geriatrics; Ph.D., M.D., Emory Univ., 1995. Age-related changes in brain function.

Gloria Borgstahl, Professor, Cancer Research Graduate Program: Ph.D., Univ IA, 1992.  Focused on structure determination (PDF) by protein crystallography and crystal growth and perfection (PDF).

Julia A. Bridge, Professor, Pathology and Microbiology; M.D., UNMC, 1984. Cytopathology, solid tumor cytogenetics and molecular diagnostics.

William G. Chaney, Professor, Biochemistry and Molecular Biology, COM, Courtesy Associate Professor, Eppley Institute; Ph.D., Michigan State University, 1979.  Biological function of complex carbohydrates.

Nora Chapman, Professor, Pathology/ Microbiology, COM; Ph.D. Harvard UN 1981.  Virology, molecular biology. Persistence of enteroviruses in myocarditis/cardiomyopathy and use of coxsackie viruses as a vector.

Pi-Wan Cheng, Professor, Biochemistry and Molecular Biology, COM, Courtesy Professor, Eppley Research Institute; Ph.D., Case Western Reserve University, 1975.  Glycobiology; gene therapy.

Judith K. Christman, Stokes Shackleford Professor and Chairperson, Biochemistry and Molecular Biology, COM, Courtesy Professor, Eppley Cancer Research and Care, Courtesy Professor, Eppley Cancer Research Institute, Member Research Training Program; Ph.D., Columbia University, 1967. Gene regulation; DNA methylation.

Pawel Ciborowski, Associate Professor, Biochemistry and Molecular Biology, and Director of Proteomics Program of CNND; Ph.D., National Institute of Hygiene, Warsaw, Poland, 1983.  Protein structure and functions; Proteomics.

Dahn L. Clemens, Associate Professor, Internal Medicine GI; Ph.D., CO St Univ., 1989.  The effects of ethanol metabolism on liver and pancreas cellular functions and replications.

Kenneth Cowan, Director, Cancer Research Graduate Program, Director, Eppley Cancer Research and Care, Professor, Eppley Research Institute, Courtesy Professor, Internal Medicine, COM, Regents/Name Chair, Eppley Research Institute; M.D. Case Western 1975, Ph.D. Case Western 1975.  Our laboratory is interested in understanding the role of tumor suppressor genes in the development of human tumors.

G. Stanley Cox, Associate Professor, Biochemistry & Molecular Biology, COM, Courtesy Associate Professor, Eppley Research Institute; Ph.D. UN-IA 1973.  Research interests are focused in the areas of molecular biology, recombinant DNA technology, and biochemical oncology, with an emphasis on mechanisms of gene expression

Terrence M. Donohue, Jr., Professor, Internal Medicine; Ph.D., UNMC, 1978. Ethanol effects on proteolytic systems in the liver.

Anna Dunaevsky, Associate Professor, Development Neuroscience, Munroe-Meyer Institute for Genetics and Rehabilitation; Ph.D., Univ of MA, 1997. Mechanisms of synaptic formation and plasticity in neurodevelopmental disorders and learning.

Howard S. Fox, Professor and Executive Vice Chair, Pharmacology and Experimental Neuroscience; Ph.D., Univ of CA, SF,1985, M.D., Univ of CA. SF, 1987. Neurodegeneration, brain dysfunction, and viral infections of the brain.

Lie Gao, Assistant Professor, Cellular and Integrative Physiology; M.D., West China Univ of Medical Sciences, China, 1984, Ph.D., Peking Union Medical College and Chinese Academy of Medical Sciences, China, 2001. Regulation of bioactivators in the RVLM on cardiovascular activity and autonomic function in normal and disease states.

Chittibabu (Babu) Guda, Associate Professor, Genetics, Cell Biology and Anatomy, Director Center for Bioinformatics and Systems Biology, Ph.D, Auburn University, 1997.  Development and application of computational methods for functional annotation of proteins, pathways, networks and systems in biomedical research.

Catherine L. Gebhart, Assistant Professor, Pathology and Microbiology; Ph.D., UNMC, 1998. Histocompatibility.

Frederick G. Hamel, Professor, Internal Medicine, Ph.D., Indiana Univ., 1983.  Degradation of insulin and its relationship to insulin's mechanism of action; polypeptide hormone metabolism; diabetes mellitus.

Duygu Dee Harrison-Findik, Associate Professor, Internal Medicine GI; Ph.D., Justus-Liebig Univ., 1989. Transcriptional regulation of antimicrobial peptide hepcidin and iron metabolism by oxidative stress in liver diseases.

Steven H. Hinrichs, Professor and Chairman, Pathology and Microbiology, Senior Associate Dean for Research; M.D., Univ of North Dakota, 1980.  Molecular pathogenesis and diagnostics of infectious organism, antimicrobial drug discovery and bioterrorism preparedness information technology.

R. Katherine Hyde, Assistant Professor, Biochemistry and Molecular Biology; Ph.D., University of Wisconsin-Madison, 2005. Control of gene expression in leukemia and normal hematopoiesis.

Peter Iwen, Professor, Pathology and Microbiology; Ph.D., University of Nebraska Medical Center, 2001.  Evaluation of multiple platforms utilizing the internal transcribed spacer regions of the rDNA complex as a molecular target for the diagnosis of invasive mycoses.

Maneesh Jain, Assistant Professor, Biochemistry and Molecular Biology; Ph.D., Institute of Microbial Technology (Jawaharlal Nehru Univeristy), India, 2002; Targeted therapy of solid tumors by antibody engineering and TME modulation.

Shantaram S. Joshi, Professor, Genetics, Cell Biology and Anatomy; Ph.D., Bombay Univ., 1979.  Biology and Therapy of human B-Cell malignancies.  Functional Genomics of human Chronic Lymphocytic Leukemia (CLL) and Cellular/Immuno therapy of human Mantle Cell Lymphoma (CLL).

Adam R. Karpf, Associate Professor, Cancer Research Graduate Program; Ph.D., University of Texas, 1997. DNA methylation, cancer epigenetics, tumor antigens, ovarian cancer.

Kusum Kharbanda, Associate Professor, Internal Medicine; Ph.D. Univ. of Delhi, India, 1988.  Alcohol Liver Study.

Tammy L. Kielian, Professor, Pathology and Microbiology; Ph.D., Univ of Kansas Medical Center, KC, 1998. Immunology of infectious diseases, focus on staphylococcus aureus colonization of the brain and biofilm growth.

David L. Klinkebiel, Assistant Professor, Biochemistry and Molecular Biology; Ph.D., Univ. of NE Lincoln, 1990.  Influence of DNA methylation on gene expression and the association with cancer development.

Robert Lewis, Professor, Cancer Research Graduate Program; Ph.D., Univ. Florida 1983. Molecular mechanisms regulating signal transduction by the insulin and IGF-1 receptors; regulation of intracellular mediators controlling cell proliferation, differentiation, and apoptosis.

David W. Li, Associate Professor, Biochemistry and Molecular Biology; Ph.D., Univ. of Washington, 1992.  Molecular and cellular mechanisms of ocular disease (cataract and retina degeneration) and cancer.

Ming-Fong Lin, Professor, Biochemistry & Molecular Biology, COM, Professor, Surgery, COM, Courtesy Professor, Eppley Research Institute; Ph.D. ST UN-NY 1983.  Our current effort is to investigate the mechanism of cell growth regulation by tyrosine phosphorylation signal transduction for understanding one mechanism of multi-step carcinogenesis of prostate epithelium.

Oksana Lockridge, Professor/Cont, Cancer Research Graduate Program, Associate Professor, Biochemistry and Molecular Biology, COM; Ph.D. Northwestern IN 1971.  More than 30 genetic variations of human butyrylcholinesterase are known. On the basis of our results with the acetyl cholinesterase knockout mouse, we are searching for genetic variants of human acetyl cholinesterase. We expect people with genetically deficient acetyl cholinesterase variants to be unusually susceptible to the toxic effects of organ phosphorus and carbamate pesticides.

Xu Luo, Associate Professor, Cancer Research Graduate Program, Ph.D.,  Univ. Texas, 1995.  Regulation of mitochondria and dependent Apoptosis.

Richard G. MacDonald, Professor, Biochemistry and Molecular Biology, COM, Courtesy Associate Professor, Eppley Research Institute; Ph.D., University of Vermont, 1981. Transmembrane signaling and regulation of cell growth.

Benita McVicker, Assistant Professor, Internal Medicine; Ph.D., UNMC, 1997.  Alcohol liver study.

Paras Mishra, Assistant Professor, Cellular and Integrative Physiology; Ph.D., Banaras University, 2006. MicroRNomics of cardiovascular diseases and diabetic cardiomyopathy.

Daniel T. Monaghan , Professor, Pharmacology and Experimental Neuroscience, COM; Ph.D. Univ of California, Irvine, 1985. Molecular mechanisms regulating NMDA receptor activity and synaptic transmission, the role of NMDA receptors in early development.

Michel M. Ouellette, Associate Professor, Cancer Research Graduate Program, Courtesy Assistant Professor, Biochemistry & Molecular Biology, COM; Ph.D. Univ Montreal 1991.  The primary focus of Dr. Ouellette’s laboratory is to understand the molecular mechanisms that determine the life span of human cells.

Babu Padanilam, Professor, Cellular and Integrative Physiology, COM; Ph.D. Medical College of Georgia 1985.  Major interest: Pathophysiology of Acute Ischemic Renal Injury.  Specialty: Cellular, biochemical and molecular approaches to study of acute renal injury.

Kaushik P. Patel, Professor, Cellular and Integrative Physiology, COM; Ph.D. Un-Western Ont 1983.  Major Interest: Neural control of circulation.  Specialty: Neural control of fluid balance in normal and disease states.

Youri I. Pavlov, Professor, Cancer Research Graduate Program; Ph.D., Univ. Leningrad, Russia, 1991.  Molecular mechanisms of immuniglobulin genes variability.

Angie A. Rizzino, Professor, Cancer Research Graduate Program, Program Leader, UNMC Eppley Cancer Center, Professor, Pathology/ Microbiology, COM, Courtesy Professor, Biochemistry and Molecular Biology, COM;; Ph.D. Suny-Stony Broo 1974.  Molecular and cellular biology of gene regulation.  The primary goal of Dr. Rizzino’s laboratory is to understand the molecular mechanisms by which differentiation regulates the transcription of genes that code for growth factors and their receptors.

Eleanor G. Rogan, Professor, Cancer Research Graduate Program; Ph.D., Johns Hopkins, 1968. Metabolic activation of polycyclic aromatic hydrocarbons and catechol estrogens to form DNA adducts, generate oncogenic mutations and initiate cancer.

Shyamal K. Roy, Professor, Obstetrics and Gynecology; Ph.D., Aiims, India, 1980. Endocrine regulation of follicular development, growth factors, signal transduction in ovarian cells and biochemistry of granulosa cells.

Steven C. Sansom, Professor, Cellular and Integrative Physiology; Ph.D., Univ. Texas, Houston, 1984. Physiological mechanisms of ion transport in the kidney.

Polina Shcherbakova, Associate Professor, Cancer Research Graduate Program; Ph.D., St Petersburg State Univ. Russia, 1992.  Mechanisms controlling genome stability in eukaryotic cells, particularly in the functions of DNA polymerases in DNA replication, repair and chromosome segregation control.

Simon Sherman, Professor and Program Director, Cancer Research Graduate Program; Ph.D., Institute-Physicians, 1978.  Modeling of biomacromolecules.

Pankaj K Singh, Associate Professor, Cancer Research Graduate Program; Ph.D., UNMC, 2007. Signal transduction in cancer, cancer metabolism and systems Biology.

Shelley Smith, Professor and Director, Molecular Genetics, Director, M.D./Ph.D. Scholars Program; Ph.D., Indiana Univ, 1978. Identification of genetic influences on developmental language and learning disorders in children.

Kaihong Su, Associate Professor, Pathology and Microbiology; Ph.D., Univ of Alabama, Birmingham, 1998. Immune regulation in autoimmune diseases and cancer therapies.

James E. Talmadge, Professor, Pathology and Microbiology; Ph.D., Washington State Univ., 1979. Tumor biology, metastasis, immunotherapy molecular and cellular immunology, hematology and oncology.

Melissa Teoh-Fitzgerald, Assistant Professor, Biochemistry and Molecular Biology; Ph.D., University of Alberta, 2005. Redox signaling in cancer epithelial-fibroblast interactions.

Kelly Trujillo, Assistant Professor, Biochemistry and Molecular Biology; Ph.D., University of Texas Health Sciences at San Antonio, 2002. Epigenetic regulation of chromatin dynamics during DNA replication.

Guangshun Wang, Assistant Professor, Pathology; Ph.D., Simon Fraser Univ., 1997.  Biomolecular NMR; structural biology; signal transduction; antimicrobial peptides.

Jing (Jenny) Wang, Associate Professor, Cancer Research Graduate Program; Ph.D., Medical College of Ohio, 1996. Molecular mechanisms and therapeutic targets of metastasis.

San Ming Wang, Associate Professor, Genetics, Cell Biology and Anatomy; M.D., Univ. of Lausanne, Switzerland, 1994. Developing and applying next-generation sequencing-based approaches to study cancer genetics.

Zhixin (Jason) Zhang, Professor, Pathology and Microbiology; Ph.D., Univ. of Alabama, Birmingham, 1997. Molecular regulation of B lineage cell development.

;