Over the 30 years of the bone marrow/stem cell transplantation program, researchers at University of Nebraska Medical Center and its hospital partner, The Nebraska Medical Center, have forged strong partnerships with researchers around the world. As a result, many patients come from all over the U.S. and world to see medical center experts.
One example of how research plays a critical role in advancing treatment and care of patients is a recent study that shed new light on T-cell lymphoma.
“We don’t see a lot of cases of this rare kind of lymphoma, so our partnership with others around the world is one way everyone can share to advance our knowledge and help patients,” said Julie Vose, M.D., chief of the Division of Hematology/Oncology. “T-cell lymphoma is more common in other parts of the world. It’s very important that we have the resources and expertise to be able to do these types of studies.”
Several clinical trials for T-cell lymphoma are ongoing.
Dr. Vose, also a physician on staff at The Nebraska Medical Center, was involved in an international study that looked at 1,300 cases of T-cell lymphoma to identify which treatments were helpful. In the United States, there are about 85,000 new cases of lymphoma annually of which about 10 percent are T-cell.
It produced surprising results.
“We found that our current treatments for T-cell aren’t very helpful and that we have to look for new treatments,” said Dr. Vose, the Neumann M. and Mildred E. Harris Professor. “We also found some new types of T-cell lymphoma from genetic information that previously hadn’t been described.”
Treatment is changing as a result of the study, she said.
“It’s important to tailor treatment since not all T-cell lymphomas are alike,” she said. “Some are aggressive, some slow growing. Some patients do better with certain combinations of therapies while others do better with other types of treatment. We need to understand why.”
In the past few years, two new drugs have been approved for T-cell lymphoma.
She said treatment of lymphomas have come a long way in 30 years, thanks to research. There are 50 different types of lymphoma.
“Physicians used to treat many lymphoma patients with the same treatments,” she said. “We didn’t understand that different types of lymphoma can benefit from different types of treatment. Now we know.”
“I am always amazed at the strength and resolve that the patients and families have while going through a very difficult treatment which sometimes means staying a long time away from home. ... As healthcare providers to transplant patients, we need to provide not only the highest quality medical care but also the highest possible personal care.”
--Julie Vose, M.D., M.B.A.
Chief of the Division of Hematology/Oncology
and Neumann M. and Mildred E. Harris Professor