Structure and Development of the Human Body Core

  1. Describe and identify the essential features of normal human anatomy at the tissue, organ, and system level.
  2. Demonstrate with an acceptable degree of manual dexterity on the normal (living) subject, the position, extent, and functional integrity of organs and systems.
  3. Identify the position and extent of normal structures in radiographs, contract studies, air studies, angiograms, echograms, cross-sections, cat scans, magnetic resonance images, and osteology materials.
  4. Describe the embryological development of organs and organ systems well enough to understand the underlying defects in major congenital malformations.
  5. State the anatomical basis of clinical procedures and pathological processes and seek anatomical solutions to a clinical problem where one exists.

Cellular Processes Core

  1. Explain the roles that each of the major cellular organelles plays in cellular function.
    Identify histologically stained tissues, cells, and cellular structures and state their major functions and components.
  2. Describe the structure and functional roles of cellular macromolecules such as DNA, RNA, proteins, and lipids.
  3. Explain how enzymes catalyze reactions within the body and the mechanisms by which agents that inhibit enzyme actions work.
  4. Describe the role that cell signal transduction plays in cell function and in diseases such as cancer. 
  5. Apply basic principles of molecular genetics to understand the pathophysiologic mechanisms of inherited diseases.
  6. Interpret pedigrees representing different modes of inheritance, such as autosomal recessive, autosomal dominant, sex-linked, and maternal and mitochondrial inheritance. 
  7. Obtain a working knowledge of the degradative and biosynthetic pathways of carbohydrates, lipids, and nucleotides. 
  8. Describe the processes by which the cell generates energy in the form of ATP by the catabolism of biomolecular fuels.
  9. Explain the biochemical basis for nutritional deficiencies and the roles that vitamins play in the synthesis/development of coenzymes.

Function of the Human Body

  1. Describe the normal physiology of the cardiovascular system 
  2. Describe the normal physiology of the kidneys and how volume homeostasis is controlled.
  3. Describe the role the kidneys play in acid/base regulation. 
  4. Describe the normal physiology of the pulmonary system and its role in acid/base regulation. 
  5. Describe how the gastrointestinal system functions and its coupling with the biochemistry of metabolism. 
  6. Describe the endocrine system and its associated biochemistry
  7. Describe the male and female reproductive systems. 
  8. Use the basic physiology learned in this core to describe pathological conditions.
  9. Describe the histology of the cardiovascular, renal, respiratory, gastrointestinal, endocrine and reproductive systems.

Neurosciences

  1. Describe and identify the essential features of the brain and spinal cored, their coverings and blood supply. 
  2. Describe the genetic and histological development of the central and peripheral nervous systems and comprehend the biological basis for human disease involving development. 
  3. Comprehend conduction of nerve impulses linking biochemical events to anatomic structure whenever possible. 
  4. State the origins, trace the anatomic pathways of sensory and motor fibers in the nervous system, and indicate the sites of termination of these fibers. 
  5. Explain the physiology of all sensations and control of movement. 
  6. State the consequences of injury to structures in the brain, spinal cord, or peripheral nervous system, or, given consequences of injury locate the most likely site of the injury
  7. Be ready to assess clinically, using the neurologic exam, the intactness of all structure or systems in the nervous system.
  8. Summarize the current state of knowledge about some aspect (neuroanatomy, neurophysiology, neurochemistry, neuropathology, neurology) of the nervous system.

Integrated Clinical Experience (M1)

  1. Discuss and demonstrate an understanding of the basic ethical and conceptual components of the physician-patient relationship.
  2. Describe the role of the physician-patient relationship in the practice of medicine as it relates to patient satisfaction and clinical outcomes.
  3. Demonstrate basic physical examination skills.
  4. Demonstrate communication skills which foster the development of an effective physician-patient relationship.
  5. Conduct an effective patient-centered interview eliciting the patient’s chief complaint, history of present illness, past medical history, social history, and family history.
  6. Elicit a complete sexual history in an efficient and sensitive manner.
  7. Elicit relevant psychosocial data in a timely fashion and demonstrate the ability to formulate a patient’s health problems in an integrated biopsychosocial framework.
  8. Discuss the basic principles and stages of normal human development and apply these principles to the physician-patient relationship.
  9. Demonstrate an understanding of the importance of the family system in health and illness.
  10. Discuss the fundamental legal and ethical bases for the concepts of confidentiality and informed consent and correctly apply these concepts in patient care situations
  11. Demonstrate competency in Basic Life Support skills.
  12. Demonstrate proficiency in written and oral communication