Structure and Development of the Human Body Core
- Describe and identify the essential features of normal human anatomy at the tissue, organ, and system level.
- Demonstrate with an acceptable degree of manual dexterity on the normal (living) subject, the position, extent, and functional integrity of organs and systems.
- Identify the position and extent of normal structures in radiographs, contract studies, air studies, angiograms, echograms, cross-sections, cat scans, magnetic resonance images, and osteology materials.
- Describe the embryological development of organs and organ systems well enough to understand the underlying defects in major congenital malformations.
- State the anatomical basis of clinical procedures and pathological processes and seek anatomical solutions to a clinical problem where one exists.
Cellular Processes Core
- Explain the roles that each of the major cellular organelles plays in cellular function.
Identify histologically stained tissues, cells, and cellular structures and state their major functions and components. - Describe the structure and functional roles of cellular macromolecules such as DNA, RNA, proteins, and lipids.
- Explain how enzymes catalyze reactions within the body and the mechanisms by which agents that inhibit enzyme actions work.
- Describe the role that cell signal transduction plays in cell function and in diseases such as cancer.
- Apply basic principles of molecular genetics to understand the pathophysiologic mechanisms of inherited diseases.
- Interpret pedigrees representing different modes of inheritance, such as autosomal recessive, autosomal dominant, sex-linked, and maternal and mitochondrial inheritance.
- Obtain a working knowledge of the degradative and biosynthetic pathways of carbohydrates, lipids, and nucleotides.
- Describe the processes by which the cell generates energy in the form of ATP by the catabolism of biomolecular fuels.
- Explain the biochemical basis for nutritional deficiencies and the roles that vitamins play in the synthesis/development of coenzymes.
Function of the Human Body
- Describe the normal physiology of the cardiovascular system
- Describe the normal physiology of the kidneys and how volume homeostasis is controlled.
- Describe the role the kidneys play in acid/base regulation.
- Describe the normal physiology of the pulmonary system and its role in acid/base regulation.
- Describe how the gastrointestinal system functions and its coupling with the biochemistry of metabolism.
- Describe the endocrine system and its associated biochemistry
- Describe the male and female reproductive systems.
- Use the basic physiology learned in this core to describe pathological conditions.
- Describe the histology of the cardiovascular, renal, respiratory, gastrointestinal, endocrine and reproductive systems.
Neurosciences
- Describe and identify the essential features of the brain and spinal cored, their coverings and blood supply.
- Describe the genetic and histological development of the central and peripheral nervous systems and comprehend the biological basis for human disease involving development.
- Comprehend conduction of nerve impulses linking biochemical events to anatomic structure whenever possible.
- State the origins, trace the anatomic pathways of sensory and motor fibers in the nervous system, and indicate the sites of termination of these fibers.
- Explain the physiology of all sensations and control of movement.
- State the consequences of injury to structures in the brain, spinal cord, or peripheral nervous system, or, given consequences of injury locate the most likely site of the injury
- Be ready to assess clinically, using the neurologic exam, the intactness of all structure or systems in the nervous system.
- Summarize the current state of knowledge about some aspect (neuroanatomy, neurophysiology, neurochemistry, neuropathology, neurology) of the nervous system.
Integrated Clinical Experience (M1)
- Discuss and demonstrate an understanding of the basic ethical and conceptual components of the physician-patient relationship.
- Describe the role of the physician-patient relationship in the practice of medicine as it relates to patient satisfaction and clinical outcomes.
- Demonstrate basic physical examination skills.
- Demonstrate communication skills which foster the development of an effective physician-patient relationship.
- Conduct an effective patient-centered interview eliciting the patient’s chief complaint, history of present illness, past medical history, social history, and family history.
- Elicit a complete sexual history in an efficient and sensitive manner.
- Elicit relevant psychosocial data in a timely fashion and demonstrate the ability to formulate a patient’s health problems in an integrated biopsychosocial framework.
- Discuss the basic principles and stages of normal human development and apply these principles to the physician-patient relationship.
- Demonstrate an understanding of the importance of the family system in health and illness.
- Discuss the fundamental legal and ethical bases for the concepts of confidentiality and informed consent and correctly apply these concepts in patient care situations
- Demonstrate competency in Basic Life Support skills.
- Demonstrate proficiency in written and oral communication
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