Eric Y.K. Fung, Ph.D.
Title: Professor
Department of Oral Biology
Address
Room: 1121
UNMC College of Dentistry
40th and Holdrege
Box 830740
Lincoln, NE 68583-0740
Telephone: (402) 472-6816
Fax: (402) 472-2551
email: efung@unmc.edu
Education:
- B.S. (Chemistry), University of Wisconsin, Oshkosh, Wisconsin
- Ph.D. (Pharmacology), The Ohio State University, Columbus, Ohio
- Teaching Responsibilities:
- Course Director, Introduction to Pharmacology (OB 401)
- Course Instructor, A Review of Biomedical/Dental Sciences (OB 471)
- Course Instructor, General Pharmacology (OB 639)
- Course Instructor, Oral Pharmacology (OB 653)
- Course Director, Advanced Dental Pharmacology (OBIO 862)
Research Interests:
- Effects of nicotine on bone-growth, remodeling and hormonal changes
- Release of bisphenol A from dental sealants
Grants:
- National Multiple Sclerosis Society, "Role of IL-12 gene expression in virus-induced encephalomyelitis." Principal Investigator: Tom Petro, Co-investigator: E. Fung. $209,708. 10/1/02 - 9/1/05.
- NIH, "Activation of NF-kB in Glial Cells and CNS of EAE," Principal Investigator: K. Pahan; Co--investigator: E. Fung. $1,023,000. 12/1/00 to 11/30/04.
Recent Publications:
- Fung, E.Y.K. and Giannini, P.J. Implications of drug dependence on dental practice management. General Dentistry 58(3):236-241, 2010.
- Saha, R.N., Ghosh, A., Palencia, C.A., Fung, Y.K., Dudek, S.M., and Pahan, K. TNF-α preconditioning protects neurons via neuron-specific up-regulation of CREB-binding protein. J Immunol 183:2068-2078, 2009.
- Roy, A., Jana, A., Yatish, K., Freidt, M.B., Fung, Y.K., Martinson, J.A., and Pahan. K. Reactive oxygen species up-regulate CD11b in microglia via nitric oxide: Implications for neurodegenerative diseases. Free Rad Bio Med 45:686-699, 2008.
- Brahmachari, S., Fung, Y.K. and Pahan, K. Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide. J Neuroscience 26(18):4930-4939, 2006.
- Roy, A., Fung, Y.K., Liu, X. and Pahan, K. Up-regulation of microglial CD11b expression by nitric oxide. J Biol Chem 281(21):14971-80, May 26, 2006. Epub2006 Mar 20. PMID 16551637 [PubMed – indexed for MEDLINE]
- Dasgupta, S., Jana, M., Zhou, Y., Fung, Y.K., Ghosh, S. and Pahan, K. Antineuroinflammatory effect of NF-κB essential modifier-binding domain peptides in the adoptive transfer model of experimental allergic encephalomyelitis. J of Immunology 173:1344-1354, 2004.
- Palmatier, M.I., Fung, E.Y.K. and Bevins, R.A. Effects of chronic caffeine pre-exposure on the conditioned and unconditioned psychomotor activity induced by nicotine and amphetamine in rats. Behavioral Pharmacology 14:191-198, 2003.
- Iwaniec, U.T., Haynatzki, G.R., Fung, Y.K., Akhter, M.P., Haven, M.C. and Cullen, D.M. Effects of nicotine on bone and calciotropic hormones in aged ovariectomized rats. J Musculoskel Neuron Interact 2(5):469-478, 2002.
Abstracts:
- Iwaniec U.T., Cullen D.M., Kosta N.M., Tanner S.J., Akhter M.P. and Fung Y.K. Effects of nicotine on cancellous bone in aged female rats. J Bone Mineral Res 15:(Supplement 1), S533, 2000.
- Crouch, L.D., Cha, A. and Fung, Y.K. Nicotine and calcitonin gene related peptide receptor mRNA expression in osteoblast-like cells. J Bone Mineral Res 16:(Supplement 1), SU236, 2001.
- Dasgupta, S., Fung, E. and Pahan, K. MEMO-binding domain (NBD) peptides inhibit the expression of proinflammatory molecules in vivo in the brain. J of Neurochemistry 85(11):AP0113, 2003.
- Sakhuja, N., Sheldon, E., Liu, C., Sharma, J., Schmid, M., Fung, E. and Nawshad, A. Nicotine is not the “smoking gun” for murine cleft palate. IADR/AADR/CADR 87th General Session and Exhibition, Miami, FL, April 1-4, 2009.
- Miller, A.R., Walker, A., Fung, E., and Giannini, P.J. The influence of substance abuse on oral health. Presented at the International Association of Dental Research Meeting, Miami, FL, April 2009.
