Ali Nawshad, Ph.D.

Ali Nawshad, Ph.D.

Dr. Ali NawshadTitle: Associate Professor (Adjunct Associate Professor, Department of Genetics, Cell Biology & Anatomy, UNMC)
Department of Oral Biology

Address
Room: 1412B
UNMC College of Dentistry
40th and Holdrege
Box 830740
Lincoln, NE 68583-0740

Telephone: (402) 472-1378
Fax: (402) 472-2551
email:

Education:

  • B.D.S The University of Dhaka, Bangladesh
  • M.D.Sc. (Oral Biology & Pathology) - The University of Queensland, Brisbane, Australia
  • Ph.D. (Oral Biology) - The University of Queensland, Brisbane, Australia
  • Research Fellow (Cell Biology) Harvard Medical School, Boston, MA, USA

Teaching Responsibilities:

  • Course Instructor, Biochemistry for Dental Students (OB 525)
  • Course Instructor, General Pathology I (OB 539)
  • Course Instructor, General Pathology II (OB 540)
  • Course Instructor, Advanced Oral Biology (OBIO 855)

Research Interests:

  • Transforming Growth Factor (TGF) ß signaling during palate development
  • Mechanisms of Epithelial-Mesenchymal Transition (EMT) by TGFß in HNSCC
  • Role of TGFß signaling during dentinogenesis

Lab Members:

Dr. Ferhat Ozturk,
Ph.D., Postdoctoral Fellow,
Telephone: 402-472-3086
email: fozturk@unmc.edu,

Mr. ChangChih Liu,
M.Sc., Research Technologist,
Telephone: 402-472-3086
email: ccliu@unmc.edu,

Ms. Xujuan Zhu,
Graduate Student,
Telephone: 402-472-3086
email: xzhu@unmc.edu,

Ms. Azadeh Jalali,
Graduate Student,
Telephone: 402-472-3086
email: ajalali@unmc.edu,

Dr. Tariq Alsmadi,
Graduate Student,
Telephone: 402-472-3086
email: talsmadi@unmc.edu,

Grants:

  • Nebraska Bankers Association Grant for Equipment, Title: "Thermo Scientific Nanodrop Spectrophotometer" PI: Ali Nawshad, 2010
  • NIH - National Institute of Dental and Craniofacial Research, Title: TGF ß 3 signaling in the development of palate. RO1 grant, 03/2008-02/2013; PI: Ali Nawshad

Recent Publications:

  • Medici, D., Nawshad, A. (2010). Type I collagen promotes epithelial-mesenchymal transition through ILK-dependent activation of NF-kappaB and LEF-1.Matrix Biol. (3):pp161-5.
  • Nawshad, A. (2008) Palatal seam disintegration: to die or not to die? That is no longer the question. Dev Dyn. (10):pp2643-56.
    S. Ahmed, C. Liu and A. Nawshad (2007): Mechanisms of palatal epithelial seam disintegration by Transforming growth factor ß3 (TGFß3). Developmental Biology.; 309; pp193-207
  • S. Ahmed and A. Nawshad (2007): Complexity in interpretation of embryonic epithelial-mesenchymal transition in response to transforming growth factor-beta signaling. Cells Tissues Organs.;185(1-3):pp131-45.
  • A. Nawshad, D. Medici, C. Liu and E.D. Hay (2007): TGFß3 inhibits E-cadherin gene expression in palate medial-edge epithelial cells through a Smad2-Smad4-LEF1 transcription complex. J Cell Sci.;120:pp1646-53.
  • D. Lagamba, A. Nawshad and E.D. Hay (2005): Microarray Analysis of Gene Expression during Epithelial-Mesenchymal Transformation Dev. Dyn. 234(1):pp132-142
  • A. Nawshad, D. LaGamba. A. Polad and E.D. Hay (2005): "Transforming Growth Factor-ß Signaling during Epithelial-Mesenchymal Transformation: Implications for Embryogenesis and Tumor Metastasis." Cells Tissues Organs;179:pp11-23
  • A. Nawshad, D. LaGamba and E.D. Hay (2004): Transforming growth factor ß (TGFß) signaling in palatal growth and epithelial-mesenchymal transformation (EMT). Arch. Oral Biol. 49(9) pp. 675-689
  • A. Nawshad, D. Lagamba, B.R. Olsen and E.D. Hay (2004): Laser capture microdissection (LCM) for analysis of gene expression in specific tissues during embryonic epithelial-mesenchymal transformation. Dev Dyn.; 230(3):pp529-34.
  • A. Nawshad and E.D. Hay (2003): TGFß3 upregulates LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development. J Cell Biol. 22;163(6):pp1291-1301

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