Focus/Projects
Advisory Board
Contact Information
Related Links
The Nebraska Center for Cellular Signaling (NCCS) was formed
in the fall of 2003 creating a Center of Biomedical Research Excellent
(CoBRE) under the IdeA program, which is funded by the National Institutes
of Health and the National Center for Research Resources. This Center,
through the collaborations of the University of Nebraska Medical Center,
Creighton School of Medicine, and the University of Nebraska-Lincoln,
will be the focal point for fostering new research initiatives dedicated
to improving the oral and dental health of Nebraskans and citizens of
other states. Junior and established researchers at these institutions
conduct innovative and collaborative research efforts supported by the
Center. This Center presents a strong mentoring environment to attract
and promote the development of promising investigators.
Focus
A number of areas within the field of cell biology are rapidly converging
on a common theme: cellular signal transduction. This is particularly
true for the fields of cell adhesion, cell motility and cancer biology.
The main focus of this Center is to bring together individuals studying
signal transduction to form an organized, cohesive group that will provide
leadership and mentoring to junior faculty interested in signaling.
Research
The project leaders of this Center share interests in cell motility, cell
adhesion, growth regulation, apoptosis, metastasis, and invasion. A thread
that ties this group together is their desire to understand signaling
pathways that impact cellular behavior as well as the underlying theme
of signaling through adhesion receptors and receptor tyrosine kinases.
Project
Leaders
DNA Damage
Leaders: Greg Oakley - UNMC
Mentors: Rick MacDonald - UNMC, Tom Petro - UNMC, Keith Johnson - UNMC
Leaders: Greg Taylor - UNMC
Mentors: Rick MacDonald - UNMC, Parmeder Mehta - UNMC
Ubiquitin Ligases
Leader: Manabu Furukawa - UNMC
Mentors: Rob Lewis - UNMC, Parmeder Mehta - UNMC
Signaling
Leader: Ming-Ying Tsai - UNMC
Mentor: Peg Wheelock - UNMC, Rob Lewis - UNMC
Colon Cancer
Leader: Jing (Jenny) Wang - UNMC
Mentor: Peg Wheelock - UNMC
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External Advisory Board
Thomas Carey, Ph.D., University
of Michigan
Karen Knudsen, Ph.D., Lanhenau
Medical Research Center
Jean Schwarzbauer, Ph.D.,
Princeton University
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Contact:
Valeta S. Creason - Wahl
Administrative Assistant
UNMC LTC 12726B
987696 UNMC
Omaha, NE 68198-7696
402-559-4682
402-559-3888 FAX
email: vcreason@unmc.edu
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Related Links
National Institutes of Health
National Center for Research Resources (NCRR)
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