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Dr. Ali Nawshad

Title: Associate Professor
NCCS Graduate

Address
Room: 44.4A
UNMC College of Dentistry
40th and Holdrege
Box 830740
Lincoln, NE 68583-0740


Oral Biology Department


Telephone: (402) 472-1378
Fax: (402) 472-2551
email: anawshad@unmc.edu

Education:

• B.D.S The University of Dhaka, Bangladesh
• M.D.Sc. (Oral Biology & Pathology) - The University of Queensland, Brisbane, Australia
• Ph.D. (Oral Biology) - The University of Queensland, Brisbane, Australia
• Research Fellow (Cell Biology) Harvard Medical School, Boston, MA, USA

Teaching Responsibilities:

• Course Instructor, Biochemistry for Dental Students (OB 525)
• Course Instructor, General Pathology I (OB 539)
• Course, Instructor, General Pathology II (OB 540)
• Course Instructor, Advanced Oral Biology (OBIO 855)

Research Interests:

• Tansforming Growth Factor (TGF) β signaling during palate development
• Mechanisms of Epithelial-Mesenchymal Transition (EMT) by TGFβ in HNSCC
• Role of TGFβ signaling during dentinogenesis

Grants:

• NIH - National Institute of Dental and Craniofacial Research - Title: TGF β 3 signaling in the development of palate. RO1 grant, 03/2008-02/2013; PI: Ali Nawshad

Recent Publications:

• S. Ahmed, C. Liu and A.Nawshad (2007): Mechanisms of palatal epithelial seam disintegration by Transforming growth factor β3 (TGFβ3). Developmental Biology.; 309; pp193-207
• S. Ahmed and A.Nawshad (2007): Complexity in interpretation of embryonic epithelial-mesenchymal transition in response to transforming growth factor-beta signaling. Cells Tissues Organs.;185(1-3):pp131-45.
• A.Nawshad, D. Medici, C. Liu and E.D. Hay (2007): TGFβ3 inhibits E-cadherin gene expression in palate medial-edge epithelial cells through a Smad2-Smad4-LEF1 transcription complex. J Cell Sci.;120:pp1646-53.
• D.Lagamba, A.Nawshad and E.D.Hay (2005): Microarray Analysis of Gene Expression during Epithelial-Mesenchymal Transformation Dev. Dyn. 234(1):pp132-142
• A.Nawshad, D. LaGamba. A. Polad and E.D.Hay (2005): "Transforming Growth Factor-β Signaling during Epithelial-Mesenchymal Transformation: Implications for Embryogenesis and Tumor Metastasis. Cells Tissues Organs;179:pp11-23
• A.Nawshad, D.LaGamba and E.D.Hay (2004): Transforming growth factor β (TGFβ) signaling in palatal growth and epithelial-mesenchymal transformation (EMT). Arch. Oral Biol. 49(9) pp. 675-689
• A.Nawshad, D.Lagamba, B.R.Olsen and E.D.Hay (2004): Laser capture microdissection (LCM) for analysis of gene expression in specific tissues during embryonic epithelial-mesenchymal transformation. Dev Dyn.; 230(3):pp529-34.
• A.Nawshad and E.D. Hay (2003): TGFβ3 upregulates LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development. J Cell Biol. 22;163(6):pp1291-1301