UNMC College of Dentistry - Departments & Centers

Dr. Eric Y.K. Fung

Title: Professor

Address
Room: 43
UNMC College of Dentistry
40th and Holdrege
Box 830740
Lincoln, NE 68583-0740

Oral Biology Department
Biomaterials Group

Telephone: (402) 472-6816
Fax: (402) 472-2551
email: efung@unmc.edu

Education:

B.S. (Chemistry), University of Wisconsin, Oshkosh, Wisconsin
Ph.D. (Pharmacology), The Ohio State University, Columbus, Ohio

Teaching Responsibilities:

Course Director, Introduction to Pharmacology (OB 401)
Course Instructor, A Review of Biomedical/Dental Sciences (OB 471)
Course Instructor, General Pharmacology (OB 639)
Course Instructor, Oral Pharmacology (OB 653)
Course Director, Advanced Dental Pharmacology (OBIO 862)

Research Interests:

Effects of nicotine on bone-growth, remodeling and hormonal changes
Release of bisphenol A from dental sealants

Grants:

National Multiple Sclerosis Society, "Role of IL-12 gene expression in virus-induced encephalomyelitis." Principal Investigator: Tom Petro, Co-investigator: E. Fung. $209,708. 10/1/02 - 9/1/05.
NIH, "Activation of NF-kB in Glial Cells and CNS of EAE," Principal Investigator: K. Pahan; Co--investigator: E. Fung. $1,023,000. 12/1/00 to 11/30/04.

Recent Publications:

Brahmachari, S., Fung, Y.K. and Paha, K. Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide. J of Neuroscience 26(18):4930-4939, 2006.
Roy, A., Fung, Y.K., Liu, X. and Pahan K. Up-regulation of microglial CD11b expression by nitric oxide. J Biological Chem 281(21):14861-80, May 26, 2006. (Epub 2006 Mar 20. PMID: 16551637 [PubMed - indexed for MEDLINE]
Dasgupta, S., Jana, M., Zhou, Y., Fung, Y.K., Ghosh, S., and Pahan, K. Antineuroinflammatory effect of NF-kB essential modifier-binding domain peptides in the adoptive transfer model of experimental allergic encephalomyelitis. The Journal of Immunology 173:1344-1354, 2004.
Palmatier, M.I., Fung, E.Y.K. and Bevins, R.A. Effects of Chronic Caffeine Pre-exposure on the Conditioned and Unconditioned Psychomotor Activity Induced by Nicotine and Amphetamine in Rats. Behavioral Pharmacology14:191-198, 2003.
Iwaniec, U.T., Haynatzki, G.R., Fung, Y.K., Akhter, M.P., Haven, M.C. and Cullen, D. M. Effects of nicotine on bone and calciotropic hormones in aged ovariectomized rats. J Musculoskel Neuron Interact 2(5):469-478, 2002.
Iwaniec. U.T., Fung, Y.K., Akhter, M.P., Haven, M.C., Nespor, S., Haynatzki, G.R. and Cullen, D.M. Effects of nicotine on bone mass, turnover, and strength in female rats. Calcified Tissue Int., 68:358-364, 2001.
Iwaniec, U.T., Fung, Y.K., Cullen, D.M., Akhter, M.P., Haven, M.C., Schmid, M. Effects of nicotine on bone and calciotropic hormones in growing female rats. Calcified Tissue International 67:68-74, 2000.
Fung, E.Y.K., Ewoldsen, N.O., St. Germain, H.A., Marx, D.B., Miaw, C.L., Siew, C., Chou, H.N., Gruninger, S.E. and Meyer, D.M. Pharmacokinetics of bisphenol A released from a dental sealant. JADA 131:51-58, 2000.

Abstracts:

Dasgupta, S., Fung, E. and Pahan, K. MEMO-binding domain (NBD) peptides inhibit the expression of proinflammatory molecules in vivo in the brain. J. of Neurochemistry 85(11):AP01-13, 2003.
Crouch, L.D., Cha, A., Fung, Y.K. Nicotine and calcitonin gene related peptide receptor mRNA expression in osteoblast-like cells. J. Bone Mineral Res. 16:(Supplement 1), SU236, 2001.
Iwaniec U.T., Cullen D.M., Kosta N.M., Tanner S.J., Akhter M.P., and Fung Y.K. Effects of nicotine on cancellous bone in aged female rats. J. Bone Mineral Res. 15:(Supplement 1), S533, 2000.