UNMC College of Dentistry - Departments & Centers

Dr. Richard A. Reinhardt

Title: Professor, Co-Director Undergraduate Periodontics, BJ & Ann Moran Professor of Periodontology

Address
Room: 131
UNMC College of Dentistry
40th and Holdrege
Box 830740
Lincoln, NE 68583-0740

Surgical Specialties Department
Bioregulation Group

Telephone: (402) 472-1287
Fax: (402) 472-5290
email: rareinha@unmc.edu

Education:

D.D.S. University of Nebraska, Lincoln, Nebraska
M.S. University of Nebraska, Lincoln, Nebraska
Ph.D. University of Nebraska Graduate College, Omaha, Nebraska

Teaching Responsibilities:

Director PERIO 553 Periodontal Therapy
Co-Director PERIO 629/630 Clinical Periodontics II
Co-Director PERIO 696 Clinical Periodontics III
Director PERIO 977M Prosthodontic & Periodontal Interelationships
Director PERIO 871 Advanced Periodontology

Research Interests:

Immunoregulation of periodontal disease and bone metabolism (cell culture and in vivo)
Effectiveness of periodontal therapy

Grants:

July 2008 to June 2009 Pharmaco-manipulation of Statin-induced Bone. Surgical Specialties Postgraduate Research Fund: Reinhardt, R.A., Killeen, A., $7,500.
July 2007 to July 2008 Pharmacol-manipulation of Statin-induced Bone. Surgical Specialties Postgraduate Reseach Fund and College of Dentistry Seed Grant: Reinhardt, R.A., Rutledge, J., $12,500.
June 2006 to December 2006 Use of Anabolic Agents Complexed with β-CD-Alen for Improved Stimulation of Local Bone Growth in the Oral Cavity. UNeMed Technology Admisory Group: Wang, D., Reinhardt, R.A., $10,000.
July 2005 to June 2007 Effect of Topically-Applied Simvastatin on Alveolar Bone Growth in Dogs. University of Nebraska Medical Center College of Dentistry Research Grant: Reinhardt, R.A., Morris, M., $5,000.
October 2004 to October 2005 Efficacy of Oral Hygiene Regimens. Effect on Supragingival Plaque, Gingivitis, Bleeding and Subgingival Microbial Counts. Waterpik Technologies, Inc: Barnes, C.M., Reinhardt, R.A., Payne, J.B, $78,045.

Recent Publications:

Mikuls, T.R., Payne, J.B., Reinhardt, R.A., Thiele, G.M., Maziarz, E., Cannella, A.C., Holers, V.M., K uhn, K.A., O'Dell, J.R. Antibody responses to Porphyromonas ginvivalis (P. gingivalis) in subjects with rheumatoid arthritis and periodontitis. Int Immunopharmacol 9:38-42, 2009.
Golub, L.M., Lee, H.M., Stoner, J.A., Sorsa, T., Reinhardt, R.A., Wolff, M.S., Ryan, M.E., Nummikoski, P.V., Payne, J.B. Subantimicrobial-dose doxycycline modulates gingival crevicular fluid biomarkers of periodontitis in postmenopausal osteopenic women. J Periodontol 79:1409-1418,2008.
Al-Salleeh, F., Beatty, M.W., Reinhardt, R.A., Petro, T.M., Crouch, L. Human Osteogenic Protein-1 Induces Osteogenic Differentiation of Adipose-derived Stem Cells Harvested From Mice. Archs Oral Biol 53:928-936,2008.
Morris, M., Lee, Y., Lavin, M.T., Giannini, P.J., Schmid, M.J., Marx, D.B., Reinhardt, R.A. Injectable Simvastatin in Periodontal Defects and Alveolar Ridges: Pilot Studies. J Periodontol 79:1465-1473,2008.
Liu, X.M., Wiswall, A.T., Rutledge, J.E., Akhter, M.P., Cullen, D.M., Reinhardt, R.A., Wang, D. Osteotropic Beta-cyclodextrin for Local Bone Regeneration. Biomaterials 29:1686-92, 2008.
Lee, Y., Schmid, M.J., Marx, D.B., Beatty, M.W., Cullen, D.M., Collins, M.E., Reinhardt, R.A. The Effect of Local Simvastatin Delivery Strategies on Mandibular Bone Formation In Vivo. Biomaterials 29:1940-9, 2008.
Bradley, J.D., Cleverly, D.G., Burns, A.M., Helm, N.B., Schmid, M.J., Marx, D.B., Cullen, D.M., Reinhardt, R.A. Cyclooxygenase-2 Inhibitor Reduces Simvastatin-induced Bone Morphogenetic Protein-2 and Bone Formation In Vivo. J Periodontal Res 43:267 73, 2007.
Walker, C., Puumala, S., Golub, L.M., Stoner, J.A., Reinhardt, R.A., Lee, H.M., Payne, J.B. Subantimicrobial Dose Doxycycline Effects on Osteopenic Bone Loss: Microbiologic Results. J Periodontol 78:1590-1601, 2007.
Liu, X.M., Lee, H.T., Reinhardt, R.A., Marky, L.A., Wang, D. Novel Biomineral-binding Cyclodextrins for Controlled Drug Delivery in the Oral Cavity. J Control Release 11;122:54-62, 2007.
Reinhardt, R.A., Stoner, J.A., Golub, L.M., Wolff, M.S., Lee, H.M., Meinberg, T.A., Lynch, J.C., Ryan, M.E., Sorsa, T., Payne, J.B. Efficacy of Sub-antimicrobial Dose Doxycycline in Post-menopausal Women: Clinical Outcomes. J Clin Periodontol 34:768-775, 2007.
Payne, J.B., Stoner, J.A., Nummikoski, P.V., Reinhardt, R.A., Goren, A.D., Wolff, M.S., Lee, H.M., Lynch, J.C., Valente, R., Golub, L.M. Subantimicrobial Dose Doxycycline Effects on Alveolar Bone Loss in Post-Menopausal Women. J Clin Periodontol 34:776-787, 2007.
Preston, R.D., Meinberg, T.A., Payne, J.B., Schmid, M.J., Lee, H.M., Golub, L.M., Marx, D.B., Reinhardt, R.A. Inflammatory Mediator Release Following Bone Grafting in Humans: A Pilot Study. J Clin Periodontol 34:797-804, 2007.
Liu, X.M., Reinhardt, R.A., Wang, D. Drug Delivery Strategies for Common Orofacial Diseases. J Drug Target 14:583-597, 2006.
Golub, L.M., Payne J.B., Reinhardt, R.A., Nieman, G. Can Systemic Disease Co-induce (Not Just Exacerbate) Periodontitis? A Hypothetical “Two-Hit” Model. J Dent Res 85:102-105, 2006.

Abstracts:

Reinhardt, R.A., Stoner, J.A., Golub, L.M., Lee, H.M., Payne J.B. GCF MMP-8 in postmenopausal women. Association with progressive attachment loss. J Dent Res 88 (Spec. Is):Abstract 2917, 2009.
Reinhardt, R.A., Stoner, J.A., Golub, L.M., Lee, H.M., Payne, J.B. Longitudinal GCF biomarkers associated with ongoing clinican attachment loss. Abstract #1006, 2008 American Academy of Periodontology Annual Session.
Chamberlain, J.M., Schieber, M.P., Byarlay, M.R., Giannini, P.J., Killeen, A.C., Marx, D.B., Reinhardt, R.A. Effect of simvastatin on guided bone regeneration. Abstract #789, 2008 JADR.
Mikuls, T.R., Payne, J.B., Reinhardt, R.A., Thiele, G.M., Maziarz, E., Cannella, A.C., Holers, V.M. Kuhn, K.A., Bergman, D.A., O'Dell, J.R. Immunity to the oral pathogen, Porphyromonas gingivalis (P. givgivalis) in subjects with rheumatoid arthritis and periodontitis. Arthritis Rheum 58(suppl), s274, 2008.
Payne, J.B., Stoner, J.A., Lee, H.M., Nummikoski, P.V., Reinhardt, R.A., Valente, R., Golub, L.M. Serum bone-resorption biomarkers: correlation with alveolar and systemic bone changes. J Dent Res 87 (Spec. Is.): Abstract 1558, 2008.
Golub, L.M., Lee, H.M., Stoner, J.A., Reinhardt, R.A., Sorsa, T., Goren, A.D., Payne, J.B. Bone-turnover markers in postmenopausal osteopenic women with periodontitis (POWP): Subantimicrobial-dose doxycycline (SDD). J Dent Res 87 (Spec. Is.): Abstract 3491, 2008.
Reinhardt, R.A., Stoner, J.A., Lee, H.M., Nummikoski, P.V., Golub, L.M., Payne, J.B. Crevicular fluid resorption marker: correlations with alveolar and systemic bone changes. J Dent Res 87 (Spec. Is.): Abstract 2909, 2008.

Service Activities:

Consultant, Veterans Administration Medical Center, Lincoln, NE
American Board of Dental Examiners, Periodontal Task Force
American Board of Dental Examiners Calibration Committee