Glaucoma pharmacology and physiology
Dr. Carol Toris and her colleagues, including Dr. Shan Fan, Dr. Vikas Gulati, and Dr. Sushma Rai, combine clinical studies and animal models to study effects of the glaucomatous disease process on fluid flow within the eye and how it can be treated with different glaucoma medications and drainage devices to lower the eye pressure. Recent studies include circadian regulation of fluid production and drainage in the eye; pressure lowering mechanisms of new glaucoma medications including rho kinase inhibitors, serotonergic agonists, combination drugs, prostaglandin analogs, and cannabinoids; development of pressure-lowering intraocular drainage devices; the impact of central corneal thickness on pressure measurements; aqueous humor dynamics in mice leading to genetic studies; and changes in aqueous humor dynamics in the developing eye.
B.A., Rockford College, Rockford, IL
M.S., University of Minnesota, St. Paul, MN
Ph.D. University of Minnesota, Minneapolis, MN
Neuroscience, University of Minnesota, Minneapolis, MN
Sabbatical, Allergan, Irvine, CA
To search for publications by this doctor, visit the National Library of Medicine website.