Research Overview
Current work in the Norgren Lab is focused on nonhuman primate genomics and genetics.The Norgren Lab and collaborators are working on the following projects:
- Rhesus macaque genome. In cooperation with several collaborators, a new rhesus genome assembly and annotation is being prepared. Illumina sequencing of both genomic DNA and mRNA has been performed. Links to sequences can be found here. This work was funded by the NIH.
- Chimpanzee genome. In preparation for a new chimpanzee assembly and annotation, Illumina sequencing of both genomic DNA and mRNA from "Clint", the reference chimpanzee, has been performed. Links to sequences can be found here.
- Marmoset genome. Illumina sequencing of both genomic DNA and mRNA is planned in the near future. Funding for this work was recently awarded by the Nebraska Research Initiative.
See this site for more information (UN-NHPGC)
Lab Members
Robert B. Norgren, Ph.D. - Director - NCRR/ORIP NHP SNP Discovery Project
Kristin Wipfler, B.S – Graduate Student
Mnirnal Maudhoo- Technician
Xiongfei Zhang- Technician
Norgren Lab in the News
- The Other Primates. Genome Technology, November 2012.
- Novel approach results in first ever rhesus macaque whole-genome array. Affymetrix Scientist Spotlight, May 2010.
- Boom Time for Monkey Research, Science, April 13, 2007.
- Monkey 'Gene Chip' Aids Medical Research. AP/FoxNews, November 29, 2005.
Norgren Lab Equipment
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| Ion Torrent Personal Genomics Machine: This is a NextGeneration nucleotide sequencing machine. It will be used for both genomic DNA sequencing as well as mRNA-seq. | Bioinformatics server for the Norgren Lab: Dell PowerEdge R900; Four Quad Six L7455Xeon, 2.13GHz, 64 GB |
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| Biomek 2000: This Liquid Handling Robot has been used extensively for high-throughput PCR. | |
