UNMC INBRE Mentors-Munroe Meyer Institute

Joyoti Arikkath, Ph.D.
Assistant Professor
E-mail: jyothi.arikkath@unmc.edu

Research Interests:  Dr. Arikkath aims to understand the molecular mechanisms that regulate neuronal structure and plasticity and elucidate how these mechanisms influence neural circuit formation and function. It is becoming increasingly clear that aberrant neural circuit formation and /or function underlies the pathology of a number of neurodevelopmental and neurodegenerative disorders. Thus, identifying core components of these pathways would provide better tools for therapeutic intervention in these devastating disorders.

For more information on Dr. Arikkath: Web Site

William B. Rizzo, Ph.D.
E-mail: wrizzo@unmc.edu 

Research Interests:  Sjogren-Larsson syndrome (SLS) is a human disease affecting children.  It has a number of symptoms, including mental retardation.  SLS is caused by mutations in the fatty aldehyde dehydrogenase gene, which is involved in the metabolism of lipids.  We are interested in discovering and characterizing mutations in this gene and how they affect SLS development and how the enzyme functions.

For more information on Dr. Rizzo: Web Site

Shelley D. Smith, Ph.D.
Professor and Interim Director
Hattie B. Munroe Molecular Genetics
E-mail: ssmith@unmc.edu

Research Interests:  Our research has focused on the identification of genes for neurodevelopmental disorders, specifically language/learning disorders and hearing loss.

For more information on Dr. Smith: Web Site