Diabetes, Endocrinology and Metabolism (DEM)

Diabetes, Endocrinology and Metabolism (DEM) Research Activities

FACULTY RESEARCH INTERESTS:

Robert G. Bennett, PhD

  • Role of relaxin in repair of fibrosis;
  • Role of insulin degrading enzyme in the pathophysiology of diabetes.

Brian Boerner, MD

  • Human pancreatic beta cell proliferation and regeneration
  • Improving management and outcomes of post-transplant diabetes

Cyrus V. Desouza, MBBS

  • Improving outcomes in diabetes and obesity patients using treatment algorithms;
  • Mechanisms of diabetes and metabolic syndrome on vascular endothelial function;
  • Role of atypical antipsychotic agents in the development of diabetes.

Whitney S. Goldner, MD

  • Improving outcomes after thyroid cancer including identifying possible environmental causes of and optimizing evaluation and treatment;
  • Improving glucose control in the hospitalized patient;
  • Consequences of morbid obesity surgery.

Frederick G. Hamel, PhD

  • Role of insulin degrading enzyme in insulin resistance caused by protease inhibitors;
  • Role of insulin degrading enzyme in the pathophysiology of diabetes. 

Jennifer L. Larsen, MD

  • Nontraditional risk factors for vascular disease after kidney transplantation;
  • Primary prevention of diabetes and its complications, particularly renal, eye, and cardiovascular disease in African Americans, Native Americans, and/or adolescents with diabetes or obesity.
  • Improving outcomes after islet, pancreas and/or kidney transplant
  • Effects of immunosuppressants on insulin resistance and islet function.

Lynn R. Mack, MD

  • Improving outcomes in women with diabetes during and after pregnancy;
  • Improving outcomes with cystic fibrosis related diabetes or bone disease;
  • Prevention and treatment of bone disease associated with transplantation.

Amy S. Neumeister, MD

  • Improving glucose control in the hospitalized patient

Vijay Shivaswamy, MBBS

  • Effects of immunosuppressants on insulin resistance and islet function;
  • Improving outcomes after islet, pancreas and/or kidney transplant.

Saraswathi Viswanathan, PhD

  • The role of adipose tissue inflammation in mediating obesity-linked metabolic disorders
  • Mechanisms involved in the hypolipidemic effects of fish oil
  • Fish oil and cyclooxygenases - interplay in adipose tissue
  • Role of nanoformulated superoxide dismutase on adipose tissue oxidative stress

DEM-related Clinical Trials

ENDOCRINOLOGY RESEARCH

Dr. Bennett
Dr. Robert Bennett, Principal Investigator on NIH-funded research study entitled "Relaxin Family Peptides and Hepatic Fibrosis"

VA "Bod Pod" diagnostics
Dr. Cyrus Desouza (center) instructs VA team on "Bod Pod" diagnostic tool for treatment of obesity.

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