Rheumatology and Immunology

Geoffrey Thiele, Ph.D.

Professor, Internal Medicine
Division of Rheumatology
Academic Offices: 
Experimental Immunology Laboratory
Wittson Hall 3006
Department of Internal Medicine
986350 Nebraska Medical Center
Omaha, NE  68198-6350         

Omaha VA Medical Center
Experimental Immunology Laboratory
Research Services 151, R321A
4101 Woolworth Avenue
Omaha, NE 68105

1979    BS  University of Nebraska Lincoln, Lincoln, Nebraska 
1985    Ph.D.  University of Nebraska Medical Center, Omaha, Nebraska

Current Hospital and Academic Appointments:
Professor in Internal Medicine, UNMC
Professor in Pathology and Microbiology, UNMC (Courtesy Appointment)
Member of Graduate Faculty, UNMC
Research Career Scientist, Omaha VA Medical Center
Director, Experimental Immunology Laboratories at the UNMC and OVAMC

Biographical Sketch:
Research Interests/Current Research (may not apply to all): Pathogenesis of autoimmunity in rheumatoid arthritis, alcoholic liver disease and atherosclerosis.

Selected Publications/Current Publications:
1. Quan LD, Purdue PE, Liu XM, Boska MD, Lele SM, Thiele GM, Mikuls TR, Dou H, Goldring SR,  Wang
    Development of a Macromolecular Prodrug for the Treatment of Inflammatory Arthritis: Mechanisms Involved
    in Arthrotropism and Sustained Therapeutic Efficacy.  Arthritis Res Ther  3:12(5); 170-183; 2010.  PMCID:
2. Mikuls TR, Sayles H, Yu F, Levan T, Gould KA, Thiele GM, Conn D, Jonas BL, Callahan LF, Smith  E,
    Brasington R, Moreland LW, Reynolds R, Bridges SL Jr.  Associations of Cigarette Smoking with
    Rheumatoid Arthritis in African Americans.  Arthritis Rheum  62(12):3560-3568; 2010. PMCID:  2995845
3. Duryee MJ, Klassen LW, Schaffert CS, Tuma DJ, Hunter CD, Garvin RP, Anderson DR and Thiele GM.
    Malondialdehyde-Acetaldehyde Adduct (MAA) is the Dominant Epitope After MDA Modification of Proteins
    in Atherosclerosis.  Free Radic Biol Med  299(3):G661-668; 2010. PMCID:  2952714
4. Thiele GM, Duryee MJ, Willis MS, Tuma DJ, Radio SJ, Hunter CD, Schaffert CS and Klassen  LW.
    Autoimmune Hepatitis Induced by Syngeneic Liver Cytosolic Proteins Biotransformed by  Alcohol 
    Metabolites.  Alcohol Clin Exp Res  34(12):2126-2136; 2010.  PMCID:  3014581
5. Mikuls TR, Fay BT, Michaud K, Sayles H, Thiele GM, Caplan L, Johnson D, Richards JS, Kerr GS, Cannon
    GW, Reimold A.  Associations of Disease Activity and Treatments with Mortality in Men with Rheumatoid
    Arthritis: Results from the VARA Registry.  Rheumatology  2010 July 21 PMC Journal-in Process
6. Anderson DA, Duryee MJ, Anchan RK, Garvin RP, Johnston MD, Porter TR, Thiele GM, and Klassen LW.
    Albumin-Based Microbubbles Bind Up-Regulated Scavenger Receptors Following Vascular Injury.  J Biol
    Chem  285(52):40645-40653; 2010.  PMCID:  3003363