Geoffrey Thiele, Ph.D.
Professor, Internal Medicine
Division of Rheumatology
Academic Offices:
Experimental Immunology Laboratory
Wittson Hall 3006
Department of Internal Medicine
986350 Nebraska Medical Center
Omaha, NE 68198-6350
Omaha VA Medical Center
Experimental Immunology Laboratory
Research Services 151, R321A
4101 Woolworth Avenue
Omaha, NE 68105
Education:
1979 BS University of Nebraska Lincoln, Lincoln, Nebraska
1985 Ph.D. University of Nebraska Medical Center, Omaha, Nebraska
Current Hospital and Academic Appointments:
Professor in Internal Medicine, UNMC
Professor in Pathology and Microbiology, UNMC (Courtesy Appointment)
Member of Graduate Faculty, UNMC
Research Career Scientist, Omaha VA Medical Center
Director, Experimental Immunology Laboratories at the UNMC and OVAMC
Biographical Sketch:
Research Interests/Current Research (may not apply to all): Pathogenesis of autoimmunity in rheumatoid arthritis, alcoholic liver disease and atherosclerosis.
Selected Publications/Current Publications:
1. Quan LD, Purdue PE, Liu XM, Boska MD, Lele SM, Thiele GM, Mikuls TR, Dou H, Goldring SR, Wang
Development of a Macromolecular Prodrug for the Treatment of Inflammatory Arthritis: Mechanisms Involved
in Arthrotropism and Sustained Therapeutic Efficacy. Arthritis Res Ther 3:12(5); 170-183; 2010. PMCID:
2990997
2. Mikuls TR, Sayles H, Yu F, Levan T, Gould KA, Thiele GM, Conn D, Jonas BL, Callahan LF, Smith E,
Brasington R, Moreland LW, Reynolds R, Bridges SL Jr. Associations of Cigarette Smoking with
Rheumatoid Arthritis in African Americans. Arthritis Rheum 62(12):3560-3568; 2010. PMCID: 2995845
3. Duryee MJ, Klassen LW, Schaffert CS, Tuma DJ, Hunter CD, Garvin RP, Anderson DR and Thiele GM.
Malondialdehyde-Acetaldehyde Adduct (MAA) is the Dominant Epitope After MDA Modification of Proteins
in Atherosclerosis. Free Radic Biol Med 299(3):G661-668; 2010. PMCID: 2952714
4. Thiele GM, Duryee MJ, Willis MS, Tuma DJ, Radio SJ, Hunter CD, Schaffert CS and Klassen LW.
Autoimmune Hepatitis Induced by Syngeneic Liver Cytosolic Proteins Biotransformed by Alcohol
Metabolites. Alcohol Clin Exp Res 34(12):2126-2136; 2010. PMCID: 3014581
5. Mikuls TR, Fay BT, Michaud K, Sayles H, Thiele GM, Caplan L, Johnson D, Richards JS, Kerr GS, Cannon
GW, Reimold A. Associations of Disease Activity and Treatments with Mortality in Men with Rheumatoid
Arthritis: Results from the VARA Registry. Rheumatology 2010 July 21 PMC Journal-in Process
6. Anderson DA, Duryee MJ, Anchan RK, Garvin RP, Johnston MD, Porter TR, Thiele GM, and Klassen LW.
Albumin-Based Microbubbles Bind Up-Regulated Scavenger Receptors Following Vascular Injury. J Biol
Chem 285(52):40645-40653; 2010. PMCID: 3003363
