Investigational Drugs, Drugs in Clinical Trials, Newly Approved Drugs
Investigational drugs/clinical trials
Recently approved drugs
New drug approval process
Searching PubMed for clinical trial results
Investigational Drugs; Drugs in Clinical Trials
- Clinical
Trials Information webpage
- Guide produced by the McGoogan Library of Medicine.
- ClinicalTrials.gov
http://www.clinicaltrials.gov
- U.S. Government supported database of ongoing clinical trials.
- IFPMA (International Federation of Pharmaceutical Manufacturers Association) Clinical Trials Portal
http://www.ifpma.org/clinicaltrials.html
- The IFPMA portal gives free access to database records concerning ongoing and completed clinical trials sponsored by pharmaceutical manufacturers.
- CenterWatch
http://www.centerwatch.org
- Another database listing ongoing clinical trials.
- Inpharma weekly
- Shelved in Journal Stacks
- Inteleos
- A database containing information about drugs in development. Contact Cindy Schmidt in the McGoogan Library's Reference Department or Lisa Worrall in The Nebraska Medical Center's Drug Information Center if you need an Inteleos search.
- Medical News on the World Wide Web
- Check the listed sites for late-breaking news items reported in the popular press. Some
of the listed sites include associated journal citations.
- NIH
Clinical Alerts website
http://www.nlm.nih.gov/databases/alerts/clinical_alerts.html
- "Clinical alerts are provided to expedite the release of findings from
the NIH-funded clinical trials where such release could significantly affect morbidity
and mortality."
- Pharmaceutical
Company Websites
- U.S. Food and Drug Administration website
http://www.fda.gov/
- See "FDA
News" for FDA press releases, information on "hot topics",
and current issues of FDA publications. You can also search
the website for information on a specific drug.
Recently Approved Drugs
- Drug Facts and Comparisons
- Reserve QV 772 F142 (looseleaf w/monthly updates); Reference Bookcase QV 772 F142 (annual)
- Inpharma weekly
- Shelved in Journal Stacks
- Medical
News Services on the World Wide Web
- Check these services for journal citations associated with late-breaking news items reported
in the popular press.
- MICROMEDEX ® Databases
- Pharmaceutical
Company Websites - check the producing company's website
- Trade Name Websites
- Pharmaceutical companies will often put up special websites for new, high profile drugs. Try
entering the drug name as part of an internet address; for example,
http://www.viagra.com/ to find company-supplied information.
- U.S. Food and Drug Administration website
http://www.fda.gov/
- See "FDA
News" for FDA press releases, information on "hot topics",
and current issues of FDA publications. You can also search
the website for information on a specific drug name.
- USP DI. Drug information for the health care professional
- Reference Bookcase QV 740 AA1 U601
- CDER Handbook
http://www.fda.gov/cder/handbook/index.htm
- Publication of the U.S. Food and Drug Administration Center
for Drug Evaluation and Research. Sections on New Drug Development
and Review, Post Drug Approval Process, Generic Drug Review, Over-the-Counter Drug Review, etc.
- From
Test Tube to Patient: New drug development in the United States
http://www.fda.gov/fdac/special/newdrug/ndd_toc.html
- A special issue of FDA Consumer magazine from January 1995, which details the drug review
and approval process, and other FDA activities.
The Medical Subject Heading (MeSH) Tree for "Clinical Trials" is
shown below. Click on one of the terms below to initiate a PubMed/MEDLINE
search that will be limited to a specific type of
clinical trial. After retrieving the results for the type of trial,
add additional search terms to the search box. For example:
"Clinical Trials"[MESH] AND ("proton pump inhibitor"
OR "proton pump inhibitors" OR PPI* OR omeprazole OR Prilosec
OR lansoprazole OR Prevacid OR rabeprazole OR Aciphex OR pantoprazole
OR Protonix OR esomeprazole OR Nexium)
Click the "Go" button. Alternately, you can perform additional
searches using relevant MeSH headings or keywords and then use the
"History" option below the search box to combine the results
of several searches using the search numbers "AND", "OR"
or "NOT" (e.g. #1 AND #2). The links provided will
provide access to PubMed with LinkOut to Full-Text (authorized users only).
"Clinical Trials" [MeSH] - exploded searches that use this term also retrieve all studies indexed with
the terms below:
"Clinical Trials, Phase I" [MeSH]
"Clinical Trials, Phase II" [MeSH]
"Clinical Trials, Phase III" [MeSH]
"Clinical Trials, Phase IV" [MeSH]
"Controlled Clinical Trials" [MeSH] - exploded searches that use this term also retrieve all records indexed
under "Randomized Controlled Trials" [MeSH]
"Randomized Controlled Trials" [MeSH]
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