Each step of screening and selection during the search for a monoclonal antibody can vary greatly, therefore projects are custom-billed for the actual use of materials and reagents. The average project price for developing a monoclonal antibody is usually between $1,500 and $2,000. An investigator can expect a time investment of 18-24 weeks (8-10 week immunization period, and 10-12 weeks culture and screening efforts), from the ordering of mice for immunization to the production of supernatant from the selected clones.
Animal Immunization: $250.00/antigen
1 antigen to 3 mice
Price includes the purchasing and housing of mice, adjuvants administered, injections and eye bleeds
Fusion: $75.00/mouse
10 plates, using 1 spleen and NS-1 myeloma partner cell line.
Sample Screening and Cell Refeeding: $1,200.00 - $1,700.00 over the course of the project
Isotyping: $32.00/cell line
The costs listed are to be used to estimate the price of services performed in the Monoclonal Antibody Facility for UNMC faculty. Non-UNMC academic users are charged an institutional overhead fee of 25% (labor costs for academic users are supported by the Nebraska Research Initiative). Corporate product development can be contracted.