The University of Nebraska Medical Center has purchased a Thermo Fisher Scientific Cellomics™ ArrayScan Vti automated fluorescent microscopic imaging system designed for high content screening and analysis of either fixed- or live-cells. High content screening (HCS) is an integration of cell based assays, robotics, high resolution fluorescent microscopy, image analysis and advanced informatics. The ArrayScan Vti features include optics by Carl Zeiss, broad white-light source, 12-bit cooled CCD camera, controller software, and live cell chamber for a complete temperature, humidity, and CO2 controlled environment. Additional features include brightfield microscopy, optical sectioning of highly complex or mixed samples, and automated emission filtering. The instrument is designed to work with image analysis modules (BioApplications, see below) that automatically convert images into numeric data that capture changes in cell size, shape, motility, kinetics, and other properties. Measurement of 60,000 cells across 96 different experimental treatments can be made in less than 15 minutes. With the integration of the ArrayScan Vti into the F3 Robotic Multi-Assay System, this enables a non-biased, unattended, round-the-clock HCS approach to study the function of genes and their ability to affect specific biological responses, and adds another valuable component to the High Throughput Screening facility’s increasing and expanding capabilities.

For more information on Cellomics / Thermo Fisher Scientific you can visit their website or the arrayscan page.