Postnatal Chromosome Analysis - High Resolution

Test name: Postnatal Chromosome Analysis – High Resolution
Also known as: Postnatal Cytogenetics, Karyotyping by G-banding

Indications:
     • Multiple congenital abnormalities with or without intellectual disability
     • Intellectual disability (ID)
     • Dysmorphic features
     • Failure to thrive
     • Short stature
     • Family history of chromosome abnormality
     • Recurrent pregnancy losses (2 or more)
     • Infertility - see also Y-Chromosome Microdeletion (YCMD) for male infertility

Test Information: Standard methodology is used for G-banded high resolution chromosome analysis.

Additional tests available on postnatal samples (refer to additional pages for details): 
     Postnatal FISH including Aneuploidy FISH and/or Constitutional (Targeted) FISH 
     180K Microarray for Congenital Anomalies/DD/Autism 
     UPD Array
     Y-Chromosome Microdeletion (YCMD) for male infertility
     Chromosome Breakage for Fanconi Anemia 
     Fragile X testing performed by the Molecular Diagnostic Section of The Nebraska Medical Center Clinical Laboratories
     Single gene testing – refer to Test Catalog for tests offered at HGL

Specimen requirements: Test kits are available – please contact the laboratory
     • Children/Adult Blood - One 2-5 ml blood sodium heparin (green top) tube 
     • Newborn Blood* - One 2-5 ml blood sodium heparin (green top) tube (minimum 1ml)
       *If ordering Microarray also for newborns a single green top tube containing at minimum 1ml blood is required

CPT codes:  88230(x2), 88261, 88280(x2), 88285(x3), 88289

Pricing: Contact the laboratory billing staff for current costs 

Shipping & Handling

Required forms: Postnatal Test Request Form

Turn-around time: Results are typically available in 7-10 days; Preliminary STAT newborn results are available in 48 hours from time of specimen arrival

Revised: 7-16-12