Test name: Y-Chromosome Microdeletion (YCMD) for male infertility
Also known as: Molecular Detection Y-Chromosome Microdeletion
- Male infertility associated with non-obstructive azoospermia or severe oligospermia
- Otherwise unexplained male factor infertility
Test Information: This testing method uses polymerase chain reaction (PCR) to detect microdeletions in the azoospermia factor (AZF) region on the Y chromosome, specifically the AZFa, AZFb, and AZFc regions. This testing identifies a Y-chromosome microdeletion in approximately 10-15% of patients with azoospermia or oligospermia.
Additional tests available related to male infertility (refer to additional pages for details):
Postnatal Chromosome Analysis (when ordered in addition to YCMD, both tests comprise the Male Infertility Panel)
Specimen requirements: Test kits are available – please contact the laboratory
- Blood: One 3-5 ml EDTA (purple top) tube
CPT codes: 83894(x5), 83900(x5), 83901(x10)*
See Postnatal Chromosome Analysis CPT codes if ordered in conjunction with YCMD, as part of Male Infertility Panel
*Unless using stored DNA from a prior sample, the following DNA Extraction codes (83891, 83894, 83907, 84311) may also apply once for molecular testing.
Pricing: Contact the laboratory billing staff for current costs
Required forms: Male Infertility Test Request Form
Turn-around time: Results are typically available in 10-14 days