Y-Chromosome Microdeletion (YCMD)

Test name:  Y-Chromosome Microdeletion (YCMD) for male infertility
Also known as: Molecular Detection Y-Chromosome Microdeletion


Indications:

  • Male infertility associated with non-obstructive azoospermia or severe oligospermia
  • Otherwise unexplained male factor infertility

Test Information:  This testing method uses polymerase chain reaction (PCR) to detect microdeletions in the azoospermia factor (AZF) region on the Y chromosome, specifically the AZFa, AZFb, and AZFc regions.  This testing identifies a Y-chromosome microdeletion in approximately 10-15% of patients with azoospermia or oligospermia.


Additional tests available related to male infertility (refer to additional pages for details):
          Postnatal Chromosome Analysis (when ordered in addition to YCMD, both tests comprise the Male Infertility Panel)


Specimen requirements:  Test kits are available – please contact the laboratory

  • Blood: One 3-5 ml EDTA (purple top) tube

CPT codes: 83894(x5), 83900(x5), 83901(x10)*
See Postnatal Chromosome Analysis CPT codes if ordered in conjunction with YCMD, as part of Male Infertility Panel
*Unless using stored DNA from a prior sample, the following DNA Extraction codes (83891, 83894, 83907, 84311) may also apply once for molecular testing.

Pricing: Contact the laboratory billing staff for current costs


Shipping & Handling 

Required forms: Male Infertility Test Request Form

Turn-around time: Results are typically available in 10-14 days

Additional links: Male Infertility Testing Flyer, Provider Fact Sheet

revised: 7-5-12

contact us

Phone:  402-559-5070 
               Option 3
800-656-3937 x95070
Fax:  402-559-7248


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