Cancer Microarray

Test name: Cancer Microarray
Also known as: Cancer Array

Indications:  Hematologic malignancies, specifically AML, ALL, CLL, CML and NHL

Test Information:

• Cancer Microarray is a test following (or used in conjunction with) chromosome analysis and/or FISH of diagnostic bone marrow, cancer blood, lymph node, or tumor tissue specimens
• A SNP/oligo platform assesses copy number changes in over 1,200 cancer-related genes and identifies copy neutral loss of heterozygosity (cnLOH) within tumor-suppressor gene regions
• This assay is particularly helpful with specimens with low mitotic index due to the disease
• This assay is unable to detect balanced translocations, or the location of duplicated or rearranged segments
• Increased resolution may identify uncertain clinical findings or unexpected abnormalities unrelated to malignancy (constitutional, consanguinity)

Specimen requirements*:  Test kits are available – please contact the laboratory
*HGL will attempt to run tests on smaller volume samples

• Bone Marrow: 3 ml bone marrow in a 3 ml sodium heparin (green top) tube
  Instructions: Bone marrow from 1^st or 2^nd aspirate using a sodium-heparinized syringe
• Cancer Blood: 3-5 ml peripheral blood in a sodium heparin (green top) tube
• Lymph Node / Solid Tumor Tissue: ≥5 mm³ of lymph node or representative tumor tissue in culture media
• Paraffin Embedded Tissue: 5-10 dissected cores from selected malignant region

CPT codes: 88237, 81406, 84311

Pricing: Contact the laboratory billing staff for current costs

Shipping & Handling 

Required forms: Oncology Test Request Form 

Turn-around time: Results are typically available in approximately 1 week 

Additional links: Educational Flyer, Provider Fact Sheet 

revised: 3-20-13