Cancer Chromosome Analysis

Test name:  Cancer Chromosome Analysis
Also known as: Cancer Cytogenetics, Karyotyping by G-banding

Indications:

• Leukemia
• Lymphoma
• Malignant hematologic disorders
• Solid tumor

Test Information: Chromosome analysis is performed using standard methodology to identify numerical and structural chromosomal aberrations with diagnostic and prognostic implications and to monitor response to therapy, disease progression, and treatment-related secondary malignancies.

Additional tests available on oncology samples (refer to additional pages for details):
     Oncology FISH
     Cancer Microarray
     Molecular Pathology at Regional Pathology Services including RT-PCR for specific neoplasms

Specimen requirements*:  Test kits are available – please contact the laboratory
*HGL will attempt to run tests on smaller volume samples 

• Bone Marrow: 2-3 ml bone marrow in a 3 ml sodium heparin tube
  Instructions: Bone marrow from 1^st or 2^ndaspirate using a sodium-heparinized syringe
• Cancer Blood: 5 ml peripheral blood in a 5 ml sodium heparin tube
• Lymph Node / Solid Tumor Tissue: ≥5 mm³ of lymph node or representative tumor tissue in tissue culture media
• Other – Body Fluid: 1-50 ml in sterile container

CPT codes:

• Bone Marrow: 88237(x2), 88261, 88280(x2), 88285(x3)
• Cancer Blood: 88237(x2), 88261, 88280(x2), 88285(x3)
• Lymph Node / Solid Tumor Tissue: 88239(x2), 88261, 88280(x2), 88285(x3)
• Other – Body Fluid: 88230, 88261, 88280(2), 88285(x3)

Pricing: Contact the laboratory billing staff for current costs  

Shipping & Handling 

Required forms: Oncology Test Request Form 

Turn-around time: 

• Bone Marrow: 2-5 days
• Cancer Blood: 2-5 days
• Lymph Node: 15-25 days
• Solid Tumor Tissue: 20-26 days
• Other – Body Fluid: 2-5 days

Additional links: Cancer Testing Services flyer  

revised: 11-2-12