Quad Screen and MS-AFP only

Quad Screen: Provides a risk assessment for Down syndrome, Trisomy 18 and neural tube defects (open spina bifida). Certain patterns of maternal serum markers may also indicate additional concerns for triploidy, Smith-Lemli-Opitz syndrome, Steroid Sulfatase Deficiency, IUFD, ventral wall defects and/or obstetrical complications.

MS-AFP only: Provides a risk assessment for neural tube defects and may indicate concern for ventral wall defects and/or obstetrical complications.

Recalculation - call 402-559-5070 option 3 in the following situations: 
• New dating information is 9 days or greater different from dating used to calculate initially. 
• Initial information provided was incomplete or incorrect regarding pregnancy or family information including but not limited to singleton vs twins, IDDM, relative with a neural tube defect, or prior child with Down syndrome.

Repeat Quad Screen or MS-AFP only: 
• If the initial specimen was drawn prior to 14 weeks 0 days OR the initial result was interpreted as a positive/high risk for open spina bifida due to a “borderline elevated level” of AFP.
• Do not repeat if the initial specimen was “positive” for Down syndrome or Trisomy 18.
• Since AF-AFP is completed with an amniocentesis at HGL, Quad Screen/MS-AFP is not recommended if amniocentesis has been completed in the current pregnancy.