AHMAD LAB PUBLICATIONS

1. Ahmad, I., Zagouras, P. and Artavanis-Tsakonas, S. (1995). Involvement of Notch-1 in mammalian retinal neurogenesis: association of Notch-1 expression with successive cell-fate determination and differentiated phenotypes. Mech. Dev. 53, 73-85.

2. Ahmad, I. (1995). Mash-1 is expressed during rod photoreceptor differentiation and binds an E-box element in the opsin promoter. Dev. Brain Res. 90, 184-189.

3. Acharya, R.H., Dooley, C.M., Thoreson, W.B., Ahmad, I. (1997). cDNA cloning and expression analysis of NeuroD in RNA in human retina.  Biochem. Biophys. Res. Commun. 233, 459-463.

4. Ahmad, I., Dooley, C. and Polk, D. (1997). Delta-1 is a regulator of neurogenesis in the vertebrate retina.  Dev. Biol. 185, 92-103.

5. Ahmad, I., Dooley, C.M. and Afiat, S. (1997). Involvement of Mash 1 in EGF mediated regulation of differentiation in the vertebrate retina. Dev. Biol. 194:86-98.

6. Ahmad I., Acharya, H.A., Rogers, J.A., Shibata, A., Smithgall, T. and Dooley C.M (1999). The role of NeuroD as a differentiation factor in the developing retina. J. Mol. Neurosci. 11, 165-178.

7. Ahmad I., Dooley C.M., Thoreson W.B., Rogers, J.A., and Afiat, S. (1999). An in vitro analysis of a mammalian retinal progenitors that gives rise to neurons and glia. Brain Res. 831, 1-10.

8. Chacko, M., Rogers, J., Turner, J.A., and Ahmad, I. (2000). Survival and differentiation of cultured retinal progenitors transplanted in subretinal space of the rat. Biochem. Biophys. Res. Commun. 268,  842-846.

9. Ahmad, I., Tang, L. and Pham, H. (2000). Identifiction of neural progenitors in the adult mammalian eye. Biochem. Biophys. Res. Commun. 270, 517-521. .

10. Ahmad, I. (2001). Stem Cells: new opportunities to treat eye diseases. Invest. Opthalmol. Vis. Sci 42: 2743-2748.

11. Zhao, X., Das, A., Thoreson, W.B., Rodriguez-Sierra, J. F. and Ahmad, I. (2002). Adult corneal limbal epithelium; a model for studying neural potential of non-neural stem cells. Dev. Biol. 250: 317-331.

12. Zhao, X., Liu and Ahmad, I. (2002). Differentiation of embryonic stem cells in retinal neurons. Biochem. Biophys. Res. Commun. 297-177-184.

13. Huang, D., Eudy, J.D., Uzvyolgyi, E., Davis, j.r., Talmadge, C.B., Pretto, D., Weston, M.D., Zhou, M., Seemayer, T.A., Ahmad, I., Kimberling, W.J., and Sumegi, J. (2002). Identification of the mouse and rat orthologues of the gene mutated in Usher syndrome type IIA (USH2A) and the cellular source of the USH2A mRNA in the retina, one of the target tissues of the disease. Genomics 80:195-200.

14. Dooley, C.M. Jackson, J., McGlade, J.C. and Ahmad, I. (2003). Involvement of Numb in vertebrate retinal development: Evidence for multiple roles of numb in neural differentiation and maturation. J. Neurobiol. 54:313-325.

15. Chacko, D.M., Das, A., Zhao, X., Jackson, J.D, Bhattacharya, S. and Ahmad, I. (2003). Transplantation of ocular stem cells: the role of injury in incorporation and differentiation of grafted cells in retina. Vision Research 43: 937-946.

16. Bhattacharya, S., Jackson, J.D., Kuszynski, C., Joshi, S. and Ahmad, I. (2003). Direct  identification and enrichment of retinal stem cells/progenitors by Hoechst dye efflux assay. Opthalmol. Vis Sci. 44:27642773.

17. James, J., Das, A.V., Bhattacharya, S., Chacko, D.M., Zhao, X. and Ahmad, I. (2003a).  In vitro generation of early born neurons from late retinal progenitors. J. Neurosci. 23: 8193-8203.

18. Ahmad, I., Das, A. V., James, J., Bhattacharya, S. and Zhao, X. (2004). Neural stem cells: types and regulation. Sem. Cell. Dev. Biol. 15:53-62.

19. Das, A.V., James, J., Zhao, X., Rahnfuhrer, J. and Ahmad, I. (2004). Identification of c-Kit receptor as a regulator of adult neural stem cells in

the vertebrate eye. Interaction with Notch signaling. Dev. Biol. 273:87-105.

20. Bhattacharya S., Dooley, C., Soto Leon, F., Madson, J. and Ahmad, I. (2004). Involvement of Ath3 in CNTF-mediated differentiation of late retinal progenitors. Mol. Cell. Neurosci. 27-43.

21. James, J., Das, A.V., Rahnfuhrer, J. and Ahmad, I. (2004). Molecular characterization of early and late retinal stem cells/progenitors by microarray analysis: regulation of proliferation and differentiation by Notch signaling J. Neurobiol. 61: 359-376.

22. Zhao, X., Das, A.V., Soto Leon, F. and Ahmad, I. (2005). Growth factor-responsive neural progenitors in post-natal mammalian retina. Dev. Dyn. 232:349-358.

23. Das, A.V., James, J., Rahnfuhrer, J., Thoreson, W.B., Bhattacharya, S., Zhao, X. and Ahmad, I. (2005). Retinal properties and potential of the adult mammalian ciliary epithelium stem cells. Vis. Res. 45:1653-66.

24. Das, A.V., Zhao, X. and Ahmad, I. (2005). Stem cell therapy for retinal degeneration: retinal neurons from heterologous sources. Sem. Ophthalmol. 20:3-10.

25. Das AV, Edakkot S, Thoreson WB, James J, Bhattacharya S, Ahmad, I. (2005). Membrane properties of retinal stem cells/progenitors. Prog. Retin. Eye Res. 24:663-81.

26. Das AV, Mallya KB, Zhao X, Ahmad F, Bhattacharya S, Thoreson WB, Hegde GV, Ahmad, I. (2006). Neural stem cell properties of Muller glia in the mammalian retina: regulation by Notch and Wnt signaling. Dev Biol. 299, 283-302.

27. Hegde GV, James J, Das AV, Zhao X, Bhattacharya S, Ahmad, I. (2007). Characterization of early retinal progenitor microenvironment: presence of activities selective for the differentiation of retinal ganglion cells and maintenance of progenitors. Exp Eye Res. 84(3):577-90.

28. Bhattacharya S, Das A, Mallya K, Ahmad, I. (2007)
Maintenance of retinal stem cells by Abcg2 is regulated by notch signaling. J Cell Sci. 120(Pt 15):2652-62.

29. Das AV, James J, Bhattacharya S, Imbalzano AN, Antony ML, Hegde G, Zhao X, Mallya K, Ahmad F, Knudsen E, Ahmad, I. (2007)
SWI/SNF chromatin remodeling ATPase Brm regulates the differentiation of early retinal stem cells/progenitors by influencing Brn3b expression and Notch signaling. J Biol Chem. 282(48):35187-201.

30. Zhao X, Das AV, Bhattacharya S, Thoreson WB, Sierra JR, Mallya KB, Ahmad, I. (2008) Derivation of neurons with functional properties from adult limbal epithelium: implications in autologous cell therapy for photoreceptor degeneration. Stem Cells. 26(4):939-49.

Book chapters:

1. Ahmad, I. (2004). Retinal Stem Cells. In Stem Cells and CNS Development (Mahendra Rao edited), 2nd Edition, Humana Press.

2. Ahmad, I. and Zhao, X. (2004) Differentiation of embryonic stem cells to retinal cells in vitro. In Embryonic Stem Cells-II: Methods and Protocols (Turksen and Walker edited). Humana Press.