Jeffrey L. Bose, Ph.D.

Department Affiliation

Biofilm development, cell-wall metabolism, virulence factor regulation

Education and Training
B.S., Bacteriology, University of Wisconsin-Madison, Madison, WI, 1999
M.S., Food Science, University of Wisconsin-Madison, Madison, WI, 2002
PhD, Microbiology, University of Georgia, Athens, GA, 2007

Notable Publications
Bose, J. L., P. D. Fey, and K. W. Bayles. 2013. Genetic tools to enhance the study of gene function and regulation in Staphylococcus aureus. Appl. Environ. Microbiol. 79:2218-2224. doi:10.1128/AEM.00136-13.

Fey, P. D., J. L. Endres, V. K. Yajjala, T. J. Widhelm, R. J. Boissy, J. L. Bose, and K. W. Bayles. 2013. A Genetic Resource for Rapid and Comprehensive Phenotype Screening of Nonessential Staphylococcus aureus Genes. mBio 4(1):e00537-12. doi:10.1128/mBio.00537-12.

Bose, J. L., and K. W. Bayles. 2012. Staphylococcus aureus. In S. Maloy and K. Hughes (eds.), Brenner's Online Encyclopedia of Genetics, 2nd Edition. Academic Press (submitted).

Kaplan, J. B., E. A. Izano, P. Gopal, M. T. Karwacki, S. Kim, J. L. Bose, K. W. Bayles, and A. R. Horswill. 2012. Low-levels of β-lactam antibiotics induce extracellular DNA release and biofilm formation in Staphylococcus aureus. mBio 3:e00198-12

Bose, J. L., M. K. Lehman, P. D Fey, and K. W. Bayles. 2012. Contribution of the Staphylococcus aureus AtlA AM and GL murein hydrolase activities in cell division, autolysis, and biofilm formation. PloS ONE 7:e42244

Pang, X., S. Moussa, N. M. Targy, J. L. Bose, N. M. George, C. Gries, H. Lopez, L. Zhang, K. W. Bayles, R. Young, and X. Luo. 2011. Active Bax and Bak are functional holins. Gene Dev. 25:2278-2290

Bose, J. L., M. S. Wollenberg, D. M. Colton, M. J. Mandel, A. N. Septer, A. K. Dunn, and E. V. Stabb. 2011. Contribution of rapid evolution of the luxR-luxI intergenic region to the diverse bioluminescence outputs of Vibrio fischeri strains isolated from different environments. Appl. and Environ. Microbiol. 77:2445-2457

Lyell, N. L., A. K. Dunn, J. L. Bose, and E. V. Stabb. 2010. Bright mutants of Vibrio fischeri ES114 reveal conditions and regulators that control bioluminescence and expression of the lux operon. J. Bacteriol. 292:5103-5114

A. N. Septer*, Bose, J. L.*, A. K. Dunn, and E. V. Stabb. 2010. FNR-mediated regulation of luminescence and anaerobic respiration in the light-organ symbiont Vibrio fischeri. FEMS Microbiol. Lett. 306:72-81 *equally contributing authors.

Lyell, N. L., A. K. Dunn, J. L. Bose, S. L. Vescovi, and E. V. Stabb. 2008. Effective mutagenesis of Vibrio fischeri using hyperactive mini-Tn5 derivatives. Appl. Environ. Microbiol. 74:7059-7063.

Bose, J. L., C. S. Rosenberg, and E. V. Stabb. 2008. Effects of luxCDABEG induction in Vibrio fischeri: Enhancement of symbiotic colonization and conditional attenuation of growth in culture. Arch. Microbiol. 190:169-183.

Bose, J. L., U. Kim, W. Bartowski, R. P. Gunsalus, A. M. Overley, N. L. Lyell, K. L. Visick, and E. V. Stabb. 2007. Bioluminescence in Vibrio fischeri is controlled by the redox-responsive regulator ArcA. Mol. Microbiol. 65:538-553

Walker, E. L., J. L. Bose, and E. V. Stabb. 2006. Photolyase confers resistance to UV light but does not contribute to the symbiotic benefit of bioluminescence in Vibrio fischeri ES114. Appl. Environ. Microbiol. 72:6600-6606.

For a complete list of publications, click here.



Jeffrey L. Bose, Ph.D.
Jeffrey L. Bose, Ph.D.
Email Address

Mailing Address
5900 Nebraska Medical Center
Omaha, NE  68198-5900

Office Location
DRC2 7076

Laboratory Location
DRC2 7054

Phone Numbers
Office: 402-559-4953
Lab: 402-559-4946