Center for Staphylococcal Research
Publications 

Mann, E. E., K. C. Rice, B. R. Boles, J. L. Endres, D. Ranjit, L. Chandramohan, L. H. Tsang, M. S. Smeltzer, A. R. Horswill, and K. W. Bayles.  2009.  Modulation of eDNA release and degradation affects Staphylococcus aureus biofilm maturation.  PLoS One.  4(6):e5822.

Beenken, K.E., Mrak, L.N., Griffin, L.M., Zielinska, A.K., Shaw, L.N., Rice, K.C., Horswill, A.R., Bayles, K.W., and Smeltzer, M.S. 2010. Epistatic relationships between sarA and agr in Staphylococcus aureus biofilm formation. PLoS ONE 5(5):e10790.

Huseby M.J., Kruse A.C., Digre J., Kohler P.L., Vocke J.A., Mann E.E., Bayles, K.W., Bohach G.A., Schlievert P.M., Ohlendorf D.H., and Earhart C.A. 2010. Beta toxin stimulates the formation of a nucleo-protein matrix in Staphylococcus aureus biofilms. PNAS. 107:14407-12

Fey, P.D.  2010.  Modality of bacterial growth presents unique targets:  how do we treat biofilm-mediated infections?  Current Opinion in Microbiology.  13:610-615.

Fey, P.D. and Olson, M.E.  2010.  Current concepts in Staphylococcus epidermidis biofilm formation.  Future Microbiol. 5: 917-933.

Chen, F., Rice, K.C., Liu, X.M., Reinhardt, R.A., Bayles, K.W., and Wang, D. 2010. Triclosan-loaded tooth-binding micelles for prevention and treatment of dental biofilm. Pharm. Res. 27:2356-64.

Ranjit, D., Endres, J., and Bayles, K.W. 2011. Staphylococcus aureus CidA and LrgA proteins exhibit holin-like properties. J. Bacteriol. 193:2468-2476.

Thurlow, L.R., Fritz, T., Angle, A., Williams, S.H., Engebretsen, I.L., Bayles, K.W., Horswill, A.R., and Kielian, T. 2011. Staphylococcus aureus biofilms prevent macrophage phagocytosis and attenuate inflammation in vivo. J. Immunol. 186:6585-6596. Image Selected for Journal Cover

Pang, X., Moussa, S., Targy, N.M., Bose, J.L., George, N.M., Gries, C., Lopez, H., Zhang, L., Bayles, K.W., Young, R., and Luo, X. 2011. Active Bax and Bak are functional holins. Genes & Develop, 25:2278-90.

Kiedrowski, M.R., Kavanaugh, J.S., Malone, C.L., Mootz, J.M., Voyich, J.M., Smeltzer, M.S., Bayles, K.W., and Horswill, A.R. 2011. Nuclease modulates biofilm formation in community-associated methicillin-resistant Staphylococcus aureus. PLoS One 6(11):e26714. 

Pozzi, C., Waters, E.M. Rudkin, J.K., Schaeffer, C, Pier, G.B., Fey, P.D., Massey, R.C., and O’Gara, J.P.  2012.  Methicillin resistance alters the biofilm phenotype and attenuates virulence in Staphylococcus aureus device-associated infections. PLoS Pathogens. Apr;8(4):e1002626.

Wang, G., Epand, R.F., Mishra, B., Lushnikova, T., Thomas, V.C., Bayles, K.W., and Epand, R.M. 2012. Decoding the Functional Roles of Cationic Side Chains of the Major Antimicrobial Region of Human Cathelicidin LL-37 Antimicrob Agents Chemother. 56:845-56.

Menousek, J., Mishra, B., Hanke, M.L., Heim, C., Kielian, T., and Wang, G. 2012. Database screening and in vivo efficacy of antimicrobial peptides against methicillin-resistant Staphylococcus aureus USA300. Int. J. Antimicrob. Agents, 39:402-406. 

Sadykov, M. and Bayles, K.W. 2012. The control of death and lysis in staphylococcal biofilms: a coordination of physiological signals. Current Opinion in Microbiology. 5:211-5.

Kaplan, J.B., Izano, E.A., Gopal, P., Karwacki, M.T., Kim, S., Bose, J.L., Bayles, K.W., Horswill, A.R. 2012. Low Levels of β-Lactam Antibiotics Induce Extracellular DNA Release and Biofilm Formation in S. aureus. MBio. 31;3(4).  

Snowden, J.R., Beaver, M., Smeltzer, M.S., and Kielian, T. 2012. Biofilm-infected intracerebroventricular shunts elicit inflammation within the central nervous system. Infect Immun., 80:3206-14, 2012. 

Bose, J.L., Lehman, M.K., Fey, P.D., and Bayles, K.W. 2012. Contribution of the Staphylococcus aureus Atl AM and GL Murein Hydrolase Activities in Cell Division, Autolysis, and Biofilm Formation.PLoS One. 7(7):e42244.

Hanke, M.L. and Kielian, T. 2012. Deciphering mechanisms of staphylococcal biofilm evasion of host immunity. Front. Cell. Inf. Microbio. 2:62.

Liu XM, Zhang Y, Chen F, Khutsishvili I, Fehringer EV, Marky LA, Bayles KW, Wang D. 2012. Prevention of orthopedic device-associated osteomyelitis using oxacillin-containing biomineral-binding liposomes. Pharm Res.29:3169–3179.

Nuxoll, A., Sadykov, M., Hanke, M., Bayles, K.W., Kielian, T., Powers, R., Fey. P.D. 2012. CcpA Regulates Arginine Biosynthesis in Staphylococcus aureus through Repression of Proline Catabolism. 2012. PLoS Pathogens 8:e1003033.

Wang, J. and Bayles, K.W. 2012. Programmed cell death in plants: lessons from bacteria? Trends Plant Sci. S1360-1385(12)00211-7.

Fey, P.D., Endres, J.L., Yajjala, V.K., Widhelm, T.J., Boissy, R.J., Bose, J.L., and Bayles, K.W. 2012. A Genetic Resource for Rapid and Comprehensive Phenotype Screening of Non-essential Staphylococcus aureus Genes. mBio. 4(1):e00537-12. doi:10.1128/mBio.00537-12. Featured Article

Hanke, M.L., Heim, C., Angle, A., Sanderson, S., and Kielian, T. 2013. Targeting macrophage activation for the prevention and treatment of S. aureus biofilm infections, J. Immunol., 190:2159-2168, 2013.

Bose, J.L., Fey, P.D., and Bayles, K.W. 2013. Genetic tools to enhance the study of gene function and regulation in Staphylococcus aureus. Applied Environ. Microbiol. 79(7):2218-2224. 

Moormeier, D.E., Endres, J.L., Mann, E.E., Sadykov, M.R., Horswill, A.R., Rice, K.C., Fey, P.D., and Bayles, K.W. 2013. The use of microfluidics technology to analyze gene expression during Staphylococcus aureus biofilm formation reveals distinct physiological niches. Applied Environ. Microbiol. 79(11):3413-24. Featured Article

Sadykov, M.R., Thomas, V.C., Marshall, D., Wenstrom, C.J., Moormeier, D.E., Widhelm, T.J., Nuxoll, A.S., Powers, R, and Bayles, K.W. 2013. Inactivation of the Pta-AckA Pathway Causes Cell Death in Staphylococcus aureus. J. Bacteriol. 195:3035-44.

Spaulding, A. R., W. Salgado-Pabon, P.L. Kohler, A.R. Horswill, D.L. Yeong, P.M. Schlievert. 2013. Staphylococcal and Streptococcal Superantigen Exotoxin Neutralization.  Clin. Micro Reviews. 26:422-447.

Olson, M.E. and A.R. Horswill. 2013.  Staphylococcus aureus Osteomyelitis: Bad to the Bone. Cell Host Microbe. 13:629-31. 

Zurek, O. W, T.K. Nygaard, R.L. Watkins, K.B. Pallister, V.J. Torres, A.R. Horswill, J.M. Voyich. 2013. The Role of Innate Immunity in Promoting SaeR/S-Mediated Virulence in Staphylococcus aureus.  J Innate Immun. Jun 29. [Epub ahead of print] 

Yang, S.J., Xiong, Y.Q., Yeaman, M.R., Bayles, K.W., Hady, W.A., and Bayer, A.S. 2013. Role of LytSR Two-Component Regulatory System in Adaptation to Cationic Antimicrobial Peptides in Staphylococcus aureus. Antimicrob. Agents Chemother. In press

Cheatle, J.*, Aldrich, A.*, Thorell, W.E., Boska, M.D., and Kielian, T. Compartmentalization of immune responses during Staphylococcus aureus cranial bone flap infection. Am J. Pathology. In press. Image Selected for Journal Cover

Gries, C.M., Bose, J.L., Nuxoll, A.S., Fey, P.D., and Bayles, K.W. 2013. The Ktr Potassium Transport System in Staphylococcus aureus and its Role in Cell Physiology, Antimicrobial Resistance, and Pathogenesis. Mol. Micro. In press.

 

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