UNMC | Projects & Investigators

CURRENT INVESTIGATORS

Paul D. Fey, Ph.D. Professor of Pathology and Microbiology Associate Medical Director of Clinical Microbiology Laboratory, The Nebraska Medical Center Dr. Fey received his training in staphylococcal biology, pathogenesis and genetics from Dr. Richard Goering (Ph.D. Creighton University 1995) and Dr. Gordon Archer (Post-doctoral fellowship Medical College of Virginia 1995-1997). Clinical microbiology training was received from both St. Joseph’s Hospital in Omaha, NE and Medical College of Virginia Hospital in Richmond, VA.
Jill K. Lindgren, B.S. (M.S. student) University of Wisconsin, Madison (Microbiology) Jill is studying the function of both copies of arginine deiminase (ADI) in S. epidermidis biofilm maturation in addition to ADI regulation by ArcR, ArgR, and Rex.
Carolyn R. Schaeffer, B.S. (Ph.D. student) University of Minnesota, Twin Cities (Biology) Carolyn is investigating the clinical and functional relevance of polysaccharide intercellular adhesin (PIA) and accumulation associated protein (Aap)-dependent S. epidermidis biofilms using relevant animal models of infection.
Austin S. Nuxoll, B.S. (Ph.D. student) University of Nebraska, Kearney (Biology) Austin is studying the metabolism and transcriptional regulation of arginine biosynthesis in S. aureus and its relationship to staphylococcal pathogenesis.
Katie L. Wilcox, B.S. (M.D./Ph.D. scholar) Doane College, Crete (Biology) S. aureus is not thought to be naturally competent and yet have orthologous genes that are known to function in competence in Bacillus subtilis. Katie is investigating the function of com genes in an ill-defined phage-mediated competence system originally defined by Dr. Peter Pattee in the 1970s.
Kendall A. Bryant, Ph.D. (Clinical Microbiology Fellow) University of Tennessee Knoxville (B.S. Microbiology) University of Nebraska Medical Center (Ph.D. Pathology and Microbiology) Kansas Department of Health-Public Health Fellowship Dr. Bryant is a clinical microbiology fellow in the CPEP program at the Nebraska Medical Center. He is currently studying the molecular epidemiology and plasmid biology of KPC-producing Enterobacter cloacae and Serratia marcescens.
Keith M. Woods, Ph.D. (Research Associate) Western Washington (B.S. Biology) Kansas State University (Ph.D. Immunology) Dr. Woods is investigating S. epidermidis vaccine candidates utilizing a rat model of catheter related infection.
Roxanne Alter, M.T. (ASCP), M.S. (Research Coordinator) University of Missouri, Kansas City (B.S. Biology) University of Nebraska Medical Center (M.T. ASCP) University of Nebraska Medical Center (M.S. Pathology and Microbiology) Roxanne coordinates several studies between the Center for Staphylococcal Research and clinical departments at UNMC. She also coordinates a study determining the prevalence of expanded-spectrum cephalosporin- and carbapenem-resistance in Enterobacteriaceae isolates from multiple clinical microbiology laboratories in Nebraska.
Cortney Halsey B.S. (Ph.D. Student) B.S. in Biology from Northern State University Cortney is studying the function of AhrC and ArgR in the regulation of arginine biosynthesis and arginine deiminase in Staphylococcus aureus.

LABORATORY ALUMNI

Wendy P. Jamison, Ph.D. Dr. Jamison studied the emergence and dissemination of blacmy-2 in Salmonella enterica serotype Typhimurium and Newport. Dissertation title (May 2005): “Molecular analysis of ceftriaxone-resistant Salmonella enterica.” She was a post-doctoral fellow at NIH Rocky Mountain Laboratories in Hamilton, MT. under the mentorship of Dr. Ted Hackstadt where she studied Chlamydia pathogenesis. She is currently an Assistant Professor in the Department of Biology at Chadron State University in Chadron, NE.
Luke D. Handke, Ph.D. Dr. Handke studied phenotypic variation in S. epidermidis and also identified several transcriptional regulators of icaADBC transcription including SarA and s^B. Dissertation title (October 2005): “Phenotypic variation of the ica operon in Staphylococcus epidermidis.” Luke accepted a post-doctoral fellowship with Dr. Linc Sonenshien at Tufts University in Boston where he studied CodY in Bacillus subtilis. Dr. Handke is currently a senior scientist with the vaccine research group at Pfizer in Pearl River, NY.
Shawn R. Slater, B.S. Shawn (pictured left with Dr. Handke) was a technolgist in the laboratory for 6 years (2002-2008) and studied biofilm maturation in S. epidermidis and molecular diagnostics of BL-3 pathogens (Yersinia pestis and Francisella tularensis). Shawn currently works for the US government at Dugway Proving grounds in Dugway, UT.
Kathie L. Rogers, Ph.D. Dr. Rogers studied class III phenotypic variation in S. epidermidis, which is a deletion event, mediated by insertion sequence elements. Dissertation title (December 2008): “Genetic characterization of class III phenotypic variation in Staphylococcus epidermidis.” Dr. Rogers, who had 20 years of experience in clinical microbiology before earning her Ph.D., is director of clinical microbiology at Jennie Edmonson Hospital in Council Bluffs, IA.
Michael E. Olson, Ph.D. Dr. Olson wrote his dissertation on genes that function to mediate biofilm maturation in S. epidermidis. His work was the basis for the current investigations on arginine catabolism. Dissertation title (April 2009): “Biofilm maturation in Staphylococcus epidermidis.” Dr. Olson is currently a post-doctoral fellow in the laboratory of Dr. Alex Horswill at the University of Iowa.
Lauren C. Kinkead, B.S. (Technologist) Minnesota State, Mankato (Microbiology) Lauren was an undergraduate summer student and technologist for three years. She studied the effects of TCA cycle mutations on the activity of bactericidal antibiotics against S. epidermidis. She is currently a PhD student in the Department of Microbiology at the University of Iowa.