Immunology, Infectious Diseases, Neuroimmunology, Juvenile Batten Disease, Glial biology, Translational therapeutics
Dr. Kielian's laboratory for more details of her research.
Education and Training
B.S., University of Nebraska-Lincoln, Lincoln NE (Biological Sciences), 1991
M.S., Kansas State University, Manhattan, KS (Immunology), 1994
Ph.D., Univ. Kansas Medical Center, Kansas City, KS (Microbiology), 1998
Post-doctoral training, Dartmouth Medical School, Lebanon, NH (Neuroimmunology), 1998-2001
Graduate students- Graduate student mentor
Advanced Immunology (PATH 955)
Bacterial Pathogenesis (PAMM 950)
Topics in Staphylococcal Biology (PAMM 950A)
Cell Signaling (BRTP 824)
Receptors and Cell Signaling (PHAR 901)
Deputy Chief Editor and Member of Editorial Board, Journal of Neurochemistry
Member of Editorial Board, Scientific Reports
Member of Editorial Board, Journal of Neuroinflammation
Jordi Folch Pi Memorial Award from the American Society for Neurochemistry (ASN) for outstanding contributions to Neuroscience Research
Full Member, NIH/NINDS NST-2 review panel for MD/PhD and K99/R00 applications, 2011-2015
Full and Ad-Hoc Member, NIH/CSR Clinical Neuroimmunology and Brain Tumors Study Section, 2002-2006
Scientific Advisory Board, UC Riverside Center for Glial NeuronalInteractions (CGNI)
UNeMed Emerging Inventor award, University of Nebraska Medical Center, 2012
UNMC Distinguished Scientist award, University of Nebraska Medical Center, 2010
Karpuk, N., Burkovetskaya, M., Fritz, T., Angle, A., and Kielian, T. Neuroinflammation leads to region-dependent alterations in astrocyte gap junction communication and hemichannel activity. J. Neurosci., 31:414-425, 2011.
Thurlow, L.R., Hanke, M.L., Fritz, T., Angle, A., Aldrich, A., Williams, S.H., Engebretsen, I.L., Bayles, K.W., Horswill, A.R., and Kielian, T. Staphylococcus aureus biofilms prevent macrophage phagocytosis and attenuate inflammation in vivo. J. Immunol., 186:6585-6596, 2011. Image Selected for Journal Cover
Hanamsagar, R., Torres, V., and Kielian, T. Inflammasome activation and IL-1/IL-18 processing are influenced by distinct pathways in microglia. J. Neurochem., 119:736-748, 2011. Selected for “In This Issue” Highlight.
Aldrich, A. and Kielian, T. Central nervous system fibrosis is associated with fibrocyte-like infiltrates. Am. J. Pathol., 179:2952-2962, 2011.
Holley, M.M. and Kielian, T. Th1 and Th17 cells regulate innate immune responses and bacterial clearance during central nervous system infection, J. Immunol., 188:1360-1370, 2012.
Karpuk, N., Burkovetskaya, M., and Kielian, T. Neuroinflammation alters voltage-dependent conductance in striatal astrocytes. J. Neurophysiol., 108: 112-123, 2012.
Hanamsagar, R., Hanke, M.L., and Kielian, T. Toll-like receptor (TLR) and inflammasome actions in the central nervous system. Trends Immunol., 33:333-342, 2012.
Hanke, M.L. and Kielian, T. Loss of MyD88-dependent signaling influences alternative macrophage activation and fibrosis during Staphylococcus aureus biofilm infection. PLoS ONE, 7(8):e42476, 2012.
For a detailed list of publications click here.
985900 Nebraska Medical Center
Omaha, NE 68198-5900