Mammalian Cell Adhesion Molecule (MCAM) database is an interactive web-based database containing cell adhesion molecules (CAMs) from the mammalian genome. The MCAM database is the first database known to be developed for CAMs and serves the community of biologists by providing the resources to search for sequence information and other details about CAMs, including function and virtual gene expression data available for normal and tumor tissues, as well as cell lines. The MCAM contains nucleotide and protein sequences of mouse, human and rat CAMs and includes Gene Ontology (GO), UniGene, UniProt, PIR, SwissProt and OMIM entries. In addition, links to GeneAtlas, GeneCards, NCBI Homologue, CGAP - Gene Finder, UniGene expression profile and GO processes and functions for each gene are provided.
The MCAM database was created exclusively for mouse adhesion molecules and the data from the mouse were used as a reference to curate the orthologs available from the human and rat. This collected information were unified as a relational database using Microsoft Access and made available online. General information about CAMs, as well as the conception and specifics of the database can be found herein. We have also provided a link to learn more about the applications of MCAM.
On the left menu, you will find the links to download and search the MCAM database.
Rakesh Singh, Ph.D.
MCAM database was developed by Anguraj Sadanandam in the Laboratory of Tumor Microenvironment led by Dr. Singh as part of a project to identify metastatic markers, which are adhesion molecules that help the cancer cells to home to a specific organ of metastasis. They were assisted by Supendar Nath Pal, Joe Ziskovisky, Prathibha Hegde and Eric Haas.