Immunology, the impact of oxidative stress on the complex virus-host-bacterium interaction occurring during influenza and MRSA co-infection.
Education and Training
Postdoctoral trainee, Immunology, Albany Medical College, NY, 2008
Ph. D, Immunology, Albany Medical College, NY, 2006
M.S., Immunology, Albany Medical College, NY, 2004
M.S., Biochemistry, Institute of Basic Medical Science, 1996
B.S., Botany, Lanzhou University, China, 1993
Sun K, Johansen FE, Eckmann L, and Metzger DW. An important role for polymeric Ig receptor-mediated transport of IgA in protection against Streptococcus pneumoniae nasopharyngeal carriage. J Immunol. 173(7):4576-81, 2004. PMCID: PMC2863832
Sun K, Salmon SL, Lotz SA, and Metzger DW. Interleukin-12 promotes gamma interferon-dependent neutrophil recruitment in the lung and improves protection against respiratory Streptococcus pneumoniae infection. Infect Immun. 75(3):1196-202, 2007. PMCID: PMC1828591
Sun K, and Metzger DW. Inhibition of pulmonary anti-Bacterial defense by IFN-g produced during recovery from influenza virus infection. Nature Med. 14(5):558-564, 2008.
Sun K, Torres L, and Metzger DW. A detrimental effect of IL-10 on protective pulmonary humoral immunity during primary influenza A virus infection. J Virol. 84:5007-14, 2010. PMCID: PMC2863832
Sun K, Ye J, Perez DR, and Metzger DW. Seasonal FluMist Vaccination Induces Cross-Reactive T Cell Immunity against H1N1 (2009) Influenza and Secondary Bacterial Infections. J Immunol. 186(2):987-93, 2011. PMCID: PMC3088159
Sun K *, Gan Y, and Metzger DW, Analysis of murine genetic predisposition to pneumococcal infection reveals a critical role of alveolar macrophages in maintaining the sterility of the lower respiratory tract. Infect Immun. 79(5):1842-7, 2011.PMCID: PMC3088159 (*corresponding author).
Metzger DW, Sun K, Immune dysfunction and bacterial coinfections following Influenza. J Immunol. 191(5):2047-52, 2013.PMCID: PMC3760235