Larisa Poluektova, MD, PhD

Larisa Poluektova








Research
Representative Publications
Biographical Information
Visit Dr. Poluektova's Laboratory

LARISA POLUEKTOVA, MD, PhD
Professor

Durham Research Center, Room 8015
985880 Nebraska Medical Center
Omaha, NE 68198-5880

Phone: 402-559-8926
E-mail: lpoluekt@unmc.edu

Keywords: hematopoietic stem cells, murine models for HIV-1, HIV-1 vaccines

Dr. Poluektova discusses how mice "are always teaching us" in the Spring 2012 issue of UNMC Discover.  Read more "Of Mice and Men.
Research Interests:
HIV-1 pathogenesis, therapeutics and vaccines, humanized mice for translational research, stem cell transplantation. The long range goals are to development small animal models to study the pathogenesis of human-specific viral co-infection - HIV-1 and HCV/HBV

top of page


Representative Publications

  1. Gorantla S, Makarov E, Roy D, Finke-Dwyer J, Murrin LC, Gendelman HE, Poluektova L. Immunoregulation of a CB2 receptor agonist in a murine model of NeuroAIDS. J. Neuroimm Pharm 2010 5(3):456-68
  2. Gorantla S, Makarov E, Finke-Dwyer J, Gebhart CL, Domm W, Dewhurst S, Gendelman HE, Poluektova LY. CD8+ cell depletion accelerates HIV-1 immunopathology in humanized mice. J. Immunol. 2010 Jun 15;184(12):7082-91
  3. Eggert D, Dash PK, Gorantla S, Dou H, Schifitto G, Maggirwar SB, Dewhurst S, Poluektova L, Gelbard HA, Gendelman HE. Neuroprotective activities of CEP-1347 in models of neuroAIDS. J Immunol.2010 Jan 15;184(2):746-56
  4. Eggert D, Dash PK, Serradji N, Dong CZ, Clayette P, Heymans F, Dou H, Gorantla S, Gelbard HA, Poluektova L, Gendelman HE. Development of a platelet-activating factor antagonist for HIV-1 associated neurocognitive disorders. Neuroimmunol. 2009 Aug 18;213(1-2):47-59
  5. Gorantla S, Liu J, Wang T, Holguin A, Sneller H, Dou H, Kipnis J, Poluektova L, and Gendelman HE. Modulation of Innate Immunity by Copolymer-1 Leads to Neuroprotection in Murine HIV-1 Encephalitis. Glia 2008 Jan 15;56(2):223-32
  6. Gorantla S, Sneller H, Walters L, Sharp JG, Pirruccello SJ, West JT, Wood C, Dewhurst S, Gendelman HE, Poluektova L. Human immunodeficiency virus type 1 pathobiology studied in humanized Balb/c-Rag2-/-γc-/- mice. J Virol. 2007 Mar;81(6):2700-12 .
  7. Gorantla S, Liu J, Sneller H, Dou H, Holguin A, Smith L, Ikezu T, Volsky DJ, Poluektova L, Gendelman HE. Copolymer-1 induces adaptive immune anti-inflammatory glial and neuroprotective responses in a murine model of HIV-1 encephalitis. J Immunol. 2007 Oct 1;179(7):4345-56

Additional publications on PubMed

top of page


Dr. Poluektova's biographical information
Visit Dr. Poluektova's laboratory

 

 

;