DONGSHENG XU, MD
Member Jialin Zheng, MD, Neuroimmunology and Regenerative Therapy Laboratory
Keywords: neural inflammation, neural progenitor cells, Epstein-Bar virus
Research Interests: Special interests in neural inflammation and neural stem cell/neural progenitor cell (NSPC) study for neurological disorders using established-well technology and experience including molecular biology/cloning, viral delivery/siRNA, neuro-electrophysiology and behavior.
Representative first author publications (past five years, *co-first authors):
Dongsheng Xu, Luwen Zhang. A novel system for production of personalized type I interferons. Biotechnology Journal, 2010; (5): 578-581.
Yong Zhao* Dongsheng Xu*, Yanjun Jiang, and Luwen Zhang. Dual functions of Interferon regulatory factors 7C in Epstein-Barr virus-mediated transformation of human B lymphocytes. PLoS One. 2010; 5(3):e9459. PMCID: PMC2831998
Dongsheng Xu, Lingjun Zhao, Luis Del Valle, J Miklossy and Luwen Zhang. Interferon regulatory factor 4 is involved in Epstein-Barr virus-mediated transformation of human B lymphocytes. J Virology 2008; 82 (13):6251-8. PMCID: PMC2447047
Yanjun Jiang*, Dongsheng Xu*, Yong Zhao and Luwen Zhang. Mutual Inhibition between Kaposi's Sarcoma-Associated Herpesvirus and Epstein-Barr Virus Lytic Replication Initiators in Dually-Infected Primary Effusion Lymphoma. PLoS ONE, 2008; 3(2):e1569. PMCID: PMC2215330
Dongsheng Xu, Jun Zhang, Tricia Coleman, Ashley Fagot, Catherine Kotalik, Lingjun Zhao and Luwen Zhang. Epstein-Barr virus inhibits Kaposis Sarcoma-associated herpesvirus lytic replication in primary effusion lymphomas. Journal of virology, 2007; 81: 6068-6078. PMCID: PMC1900272
Dongsheng Xu, Kristen Brumm, and Luwen Zhang. The latent membrane protein 1 of Epstein-Barr virus primes EBV latency cells for type I interferon production. J Biological Chem. 2006; 281(14): 9163-9.
Dongsheng Xu, Angela Buehner, Ben Miller, Jianping Xu, Travis Lambert, Laura Meyerle, Casey Nekl, Merlyn Nielsen, You Zhou. A polymorphic glucocorticoid receptor in a mouse population may explain inherited altered stress response and increased anxiety-type behaviors. FASEB Journal. 2006; 20(13): 2414-62.