Matthew Kelso, Pharm.D., Ph.D.

Matthew Kelso, Pharm.D., Ph.D.

KelsoAssistant Professor
Department of Pharmacy Practice
College of Pharmacy
University of Nebraska Medical Center
986045 Nebraska Medical Center
Omaha NE 68198-6045
402-552-6836 - Office
402-552-6095 - Lab
402-559-5673 - Fax
mkelso@unmc.edu
 
Teaching Activities
Dr. Kelso teaches Introduction to Drug Information (PHPR 562) and Pharmacotherapy IV (PHPR 678).

Research Activities/Interests
Dr. Kelso’s primary research interest is the pathophysiology and treatment of traumatic brain injury (TBI).  Dr. Kelso’s lab utilizes in vitro and in vivo models of TBI to study the biochemical mechanisms that are affected by the mechanical trauma.  New drug treatment can then be directed at these biochemical mechanisms with the goal of protecting neurons from degeneration and ultimately improving functional outcomes.
 
Recent Publications  

  1. Kelso ML, Scheff NN, Scheff SW, Pauly JR. Melatonin and minocycline for combinatorial therapy to improve functional and histopathological deficits following traumatic brain injury. Neurosci Lett. 2011 Jan 13;488(1):60-4.
  2. Kelso ML, Pauly JR. Chapter 3--Therapeutic targets for neuroprotection and/or enhancement of functional recovery following traumatic brain injury. Prog Mol Biol Transl Sci. 2011;98:85-131.
  3. Morris SA, Kelso ML, Liput DJ, Marshall SA, Nixon K. Similar of withdrawal severity in adolescents and adults in a rat model of alcohol dependence.  Alcohol. 2010 Feb;44(1): 89-98. 
  4. Nixon K, Morris SA, Liput DJ, Kelso ML. Roles of neural stem cells and adult neurogenesis in adolescent alcohol use disorders.  Alcohol. 2010 Feb;44(1): 39-56.
  5. Kelso ML, Scheff SW, Pauly JR, Loftin CD. Effects of genetic deficiency of cyclooxygenase-1 or cyclooxygenase-2 on functional and histological outcomes following traumatic brain injury in mice. BMC Neurosci. 2009 Aug 31;10:108.
  6. Kelso ML, Wehner JM, Collins AC, Scheff SW, Pauly JR. The pathophysiology of traumatic brain injury in alpha7 nicotinic cholinergic receptor knockout mice.  Brain Res.  2006 Apr 14;1083(1):204-10.