Matthew Kelso, Pharm.D., Ph.D.

Assistant Professor

Department of Pharmacy Practice
College of Pharmacy
University of Nebraska Medical Center
986045 Nebraska Medical Center
Omaha NE 68198-6045
402-552-6836 - Office
402-552-6095 - Lab
402-559-5673 - Fax
mkelso@unmc.edu
 
Teaching Activities:
Dr. Kelso teaches Introduction to Drug Information (PHPR 562), Pharmacotherapy IV (PHPR 678), Pharmaceutical Sciences II (PHSC 670) and Pharmaceutical Sciences III (PHSC 672).

Research Activities/Interests:
Dr. Kelso’s primary research interest is the pathophysiology and treatment of traumatic brain injury (TBI).  Dr. Kelso’s lab utilizes in vitro and in vivo models of TBI to study the biochemical mechanisms that are affected by the mechanical trauma.  New drug treatment can then be directed at these biochemical mechanisms with the goal of protecting neurons from degeneration and ultimately improving functional outcomes.
 
Recent Publications:

  1. Kelso ML and Oestreich JH. 2012. Traumatic brain injury: central and peripheral role of alpha7 nicotinic acetylcholine receptors. Curr Drug Targets. 13(5): 631-6.
  2. Kelso ML, Liput DJ, Eaves DW, Nixon K. 2011. Upregulated vimentin suggests new areas of neurodegeneration in a model of an alcohol use disorder. Neuroscience. 197: 381-393.
  3. Boulet T, Kelso ML, Othman SF. 2011. Microscopic magnetic resonance elastography of traumatic brain injury model. J Neurosci Methods. 201(2): 296-306.
  4. Kelso ML and Pauly JR. 2011. Therapeutic targets for neuroprotection and/or enhancement of functional recovery following traumatic brain injury. Prog Mol Biol Transl Sci. 98: 85-131.
  5. Kelso ML, Scheff NN, Scheff SW, Pauly JR. 2011. Melatonin and minocycline for combinatorial therapy to improve functional and histopathological deficits following traumatic brain injury. Neurosci Lett. 488(1): 60-64.
  6. Morris SA, Kelso ML, Liput DJ, Marshall SA, Nixon K. 2010. Similarity of withdrawal severity in adolescents and adults in a rat model of alcohol dependence.  Alcohol. 44(1): 89-98.
  7. Nixon K, Morris SA, Liput DJ, Kelso ML. 2010. Roles of neural stem cells and adult neurogenesis in adolescent alcohol use disorders.  Alcohol.44(1): 39-56.
  8. Kelso ML, Scheff SW, Pauly JR, Loftin CD. 2009. The effects of cyclooxygenase null mutation on functional and histological outcomes following controlled cortical impact brain injury. BMC Neurosci. 10(1): 108.
  9. Kelso ML, Wehner JM, Collins AC, Scheff SW, Pauly JR. 2006. The pathophysiology of traumatic brain injury in alpha7 nicotinic cholinergic receptor knockout mice. Brain Res. 1083(1): 204-10. 

Matt Kelso, Pharm.D., Ph.D.
Dr. Kelso
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