Alexey Krasnoslobodtsev, Ph.D.

Research Assistant Professor

Department of Pharmaceutical Sciences
College of Pharmacy
University of Nebraska Medical Center
986025 Nebraska Medical Center
Omaha, NE 68198-6025
402-559-1973 (Lab)
402-559-9543 (Fax)
akrasnos@unmc.edu

Research Activities/Interests:

Dr. Krasnoslobodtsev’s research interests lie at the interface of material science, biology and physical chemistry. His research program uses principles of these disciplines to answer fundamental questions of biology that can facilitate therapeutic development and early diagnostics. Specific examples of the research projects are: single molecule studies of molecular mechanisms of protein misfolding phenomenon and protein-protein interactions; combination of nanoimaging and nanomanipulation with spectroscopic techniques and development of hybrid biosensing nano-platforms with high sensitivity.

Recent Publications:

  1. Alexey V. Krasnoslobodtsev,  Jie Peng, Josephat M. Asiago, Jagadish Hindupur, Jean-Christophe Rochet and Yuri L. Lyubchenko, ” Effect of spermidine on misfolding and interactions of alpha-synuclein”, PLoS ONE, 2012, 7(5), e38099.
  2. Alexander Portillo, Alexey V. Krasnoslobodtsev and Yuri L. Lyubchenko, “Effects of electrostatics on aggregation of prion protein Sup35 peptide”, Journal of Physics Condensed Matter, 2012, 24 (16), 164205-164215.
  3. Alexey V. Krasnoslobodtsev, Jie Peng, Ivan L. Volkov, Jean-Christophe Rochet and Yuri L. Lyubchenko, ”AFM nanoprobing of alpha-synuclein self-assembly”, Journal of Nanomedicine and Nanotechnology, 2012, 3(1), 43.
  4. Alexey V. Krasnoslobodtsev, Alexander M. Portillo, Tanja Deckert-Gaudig, Volker Deckert and Yuri L. Lyubchenko, “Nanoimaging for prion related diseases”, Prion, 2010, 4(4), 265-274.
  5. Yuri L. Lyubchenko, Bo-Hyun Kim, Alexey V. Krasnoslobodtsev and Junping Yu, “Nanoimaging for protein misfolding diseases”, Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2010, 2(5), 526-543.
  6. Mikhail A. Karymov, Alexey V. Krasnoslobodtsev and Yuri L. Lyubchenko, “Stability of synaptic SfiI – DNA complex: Single molecule fluorescence analysis, Biophysical Journal, 2007, 92(9), 3241-50.
  7. Alexey V. Krasnoslobodtsev, Luda S. Shlyakhtenko and Yuri L. Lyubchenko, “Probing interactions within the synaptic DNA-SfiI complex by AFM force spectroscopy, J. Mol. Biol., 2007, 365, 1407-1416.
  8. Alexey V. Krasnoslobodtsev and Sergei N. Smirnov, Surface-Assisted Transient Displacement Charge Technique. I. Photoinduced Charge Transfer in Self-Assembled Monolayers”, J. Phys. Chem. B, 2006, 110 (36), 17931-17940.
  9. Alexey V. Krasnoslobodtsev and Sergei N. Smirnov, Surface-Assisted Transient Displacement Charge Technique. II. Effect of Gases on Photoinduced Charge Transfer in Self-Assembled Monolayers”, J. Phys. Chem. B, 2006, 110 (36), 17941-17948.
  10. Alexey V. Kransnoslobodtsev, Luda S. Shlyakhtenko, Egor Ukraintsev, Tatyana O. Zaikova, John F. W. Keana and Yuri L. Lyubchenko, “Nanomedicine and Protein Misfolding Diseases, Nanomedicine, 2005, 1(4), 300-305.

Alexey Krasnoslobodtsev, Ph.D.
Dr. Krasnoslobodtsev
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