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Funding

• Co-Investigator, “Breast Cancer Therapy with Annexin II Nanoparticles” DOD CDMRP, Breast Cancer Program, Concept Award, BC033501, $75,000 (direct) 10/1/2004-9/30/2005 (PI: J. K. Vishwanatha).

• Principal Investigator, A method to inhibit reperfusion injury in cerebral stroke, Technology Advancement Group of UNMC, $18,972 (direct).
  October 1, 2004 to January 31, 2005.

• Principal Investigator, “TAT-conjugated nanoparticles for CNS delivery of anti-HIV drugs”, National Institutes of Health, 1R21MH67525-01A2, $300,000 (direct). December 1, 2003 to November 30, 2005. (Co-investigator: Anuja Ghorpade).

• Research Contract from Pharmaceutical Company, $100,000. January 2003-

• Mentor, Summer student fellowship to Erin Neilson, Howard Hughes Medical Institute Summer Research Fellowship, $3,250. May-July 2003.

• Principal Investigator, “Intrarticular SLPI Therapy for Rheumatoid Arthritis”, National Institutes of Health, R21 AR 48399-01, $147,000.  October 1, 2001 to September 30, 2004. (Co-investigators: Kevin Garvin, Dennis Robinson, Consultants: Alexander Kabanov, James R. O’Dell). (10% efforts)
   

• Principal Investigator of subcontract, “Oral Antisense Therapy for Cancer”, National Institutes of Health (STTR-Phase I), $89,650. (UNMC $50,000) April 1, 2002 to March 30, 2003 (10% efforts). (PI: Muthiah Manoharan, ISIS Pharmaceuticals).  

• Principal Investigator of the Subproject: "Biodegradable Nanospheres for Gene Delivery", Nebraska Research Initiative, Gene Therapy Program.  Total $1,846,151 (Total for Four Projects, Each Project $461,538). July 1, 1998-June 30, 2004 (10% effort). (Program Director: Pi-Wan Cheng).

• Principal Investigator, “Magnetic Nanoparticles for Biomedical Applications”, Nebraska Research Initiative, $322,825 (direct). July 1, 2002 to June 2004 (PI: Diandra Leslie-Pelecky of University of Nebraska, Lincoln)

•  Mentor, Postdoctoral Fellowship for Dr. Sanjeeb K. Sahoo, Micellar “Nanosystem” for Localized Arterial Delivery of Rapamycin to Inhibit Restenosis, American Heart Association, Heartland Affiliate, $85,385 (direct), July 1, 2002- June 30,2004.

• Mentor, Minority summer student fellowship, Supplement to the grant “Intrarticular SLPI Therapy for Rheumatoid Arthritis”, National Institutes of Health, R21 AR 48399-01, $ 8,880 (direct).  June 1, 2002 to August 2004.

• Principal Investigator, "Biodegradable Sustained Release Nanoparticles for Restenosis". National Institutes of Health, R29 HL 57234,  $402,006, June 1997-June 2002 (50% effort).

• Predoctoral Traineeship to Swayam Prabha, Nanoparticle Mediated p53 Gene Therapy for Breast Cancer, Department of Defense, $66,000.  March 15, 2002 to Feb 15, 2005.

• Pre-doctoral Fellowship to Jayanth Panyam, Site-specific Drug Therapy to Inhibit Restenosis, American Heart Association, Heartland Affiliate, $71,000 July 1, 2001 to June 30, 2004.

• Principal Investigator, Educational Grant from Merck Pharmaceuticals, $1,000 (2000-01).  

• UNMC Graduate Fellowship to Jayanth Panyam, “Site-Specific Drug Therapy for Restenosis”, $14,500, July 2000-June 2001.

• UNMC Graduate Fellowship to Sinjan De, “Nanospheres for Oral Delivery of anti-HIV Drugs”, $43,500, July 1999-June 2002.

• Co-investigator, “VP-DSC”, Nebraska Foundation, $67,000 (PI: Luis Marky).

• Co-investigator, “Circular Dichroism-Stopped Flow Spectrometer”, National Institutes of Health, RR 13660, $117,000, April 15, 1999 to April 14, 2000.  (PI: Luis Marky)

• Co-Principal Investigator, "Development of a Novel Method to Treat Prosthetic Device Infections". Translational Seed Grant, UNMC $15,000. July 1, 1998-June 30, 1999. (Co-PI: Mark E. Rupp). (10% effort).

• Principal Investigator, “A Novel Drug Delivery Approach for the Enhanced Passage of HIV- I Protease Inhibitors through the Blood-Brain Barrier". Seed Grant, UNMC $15,000. July 1, 1998-June 30, 1999 (Co-PI: DW Miller) (10% effort).

• Principal Investigator, “DAWN^®: A Digital Signal Processing Light Scattering Detector for Molecular Characterization”. Nebraska EPSCoR, $23,800, 1998 (equipment).

• Principal Investigator, “Emulsiflex^®: a High-Pressure Homogenizer”.  UNMC, $11,000, 1998 (equipment).

• Summer Research Fellowship to Leena Mohapatra, “Formulation of Biodegradable Nanospheres for Local Intravascular Drug Delivery to Inhibit Restenosis”. American Heart Association, Heartland Affiliate,  $1,500, 1998.

• Minority Students Fellowship to Kristin Kim, “Formulation of Nanoparticles for Anti-HIV Agents”, 2,400, 1998.

• Summer Research Fellowship to Jeff Burger, American Heart Association, Michigan Affiliate, $2,400, 1996.

• Co-Principal Investigator, "Direct Osteoconductive Gene Transfer" Matrigen, Inc., Ann Arbor, MI.  $153,550, 1995-97. PI: RJ Levy (20% effort)

• Co-Principal Investigator, "Tyrosine Kinase Inhibitors in Nanoparticles for Restenosis" ParkeDavis/Warner Lambert, Ann Arbor, MI. $18,000, 1995-97. PI: RJ Levy (20% effort)

• Co-Principal Investigator, "Myocardial Controlled-Release Implants for Arrhythmias". National Institutes of Health. $ 731,264, 1995-97.  PI: RJ Levy. (50% effort)

• Principal Investigator (Subcontract), "Protected Nanoparticles for an Oral Single-Dose Staphylococcal Enterotoxin B Vaccines". Phase I SBIR, Total $69,902, Subcontract: $23,301 U.S. Department of Defense, 1995-96. (30% effort)

• Summer Biomedical Research Fellowship, University of Michigan to Jay Yang, $2,400 (1995).

• Co-Principal Investigator, "Nanoparticle Dosage Forms for the NeoRx Biostent and Related Therapeutic Concepts". $222,719, NeoRx Corporation, Seattle, WA, 1994-97. PI: RJ Levy (15% effort)

• Principal Investigator, "Iontophoretic Cardiac Implant for Antiarrhythmic Agents". $55,835, American Heart Association, MI, 1994-96. (30% effort)

• Co-Principal Investigator, "Endocardial Matrix-Electrode Implant Studies: Factors Affecting Long term usage”. $263,769, Cardiac Pacemakers, Inc., MN, 1993 –97. PI: RJ Levy (20% effort)

• Co-Investigator, “Prevention of Postoperative Arterial Fibrillation Using Epicardial Sustained Release”. $94,187, Upjohn Company, Kalamazoo, MI, 1993-95. PI: RJ Levy (15% effort)

• Co-Principal Investigator,“Artilide Polymeric Controlled Release”. $123,688, Upjohn Company, Kalamazoo, MI, 1993-95. PI: RJ Levy (15% effort)

• Co-Principal Investigator, “Development of Controlled Delivery Systems for Birth Control Vaccine”. Rs 4,860,000 (equivalent to $285,882), Department of Biotechnology, Government of India, 1990-93. PI: GP Talwar (30% effort)

• Co-Investigator, “Development of Rapid Tests for the Detection of Enteric Pathogens”. Rs 650,000 (equivalent to $38,235), Ministry of Science and Technology, Government of India, 1990-93. PI: GP Talwar (10% effort)