PSGP Curriculum

The Pharmaceutical Sciences Graduate Program is intended for those who wish to pursue a program of study leading to the Master of Science or Doctor of Philosophy degrees.

Course Requirements- The course of study for M.S. and Ph.D. students will be determined by the advisory or supervisory committee, respectively.

PHARMACEUTICAL SCIENCES (PHSC)

820 SELECTED TOPICS IN THE PHARMACEUTICAL SCIENCES, 1-2 cr I, II. A detailed study of specific subject areas related to the pharmaceutical sciences. Evaluation and discussion of the scientific literature is an integral part of the course. Prereq: Permission of instructor. Offered: Every semester. Instructor: Advisor

821 ORGANIC CHEMISTRY AND APPLICATIONS TO BIOMOLECULES, 2 cr. This course deals with the basic principles to understand the structure, reactivity, and synthesis of bioactive organic molecules. Prereq: Permission of Instructor. Offered: Even years. Instructor: Yuxiang Dong, Ph.D.
  
825 OPHTHALMIC DRUG DISCOVERY, 3 cr even yrs. This course will survey ocular diseases, their pathogenesis, current drug treatment, and approaches to the development of drug treatment.  Special methods for the evaluation of ocular drugs as well as use of animal models will be included. Prereq: Biochemistry, Permission of Instructor. Offered: Varies. Instructor: Peter Kador, Ph.D.

830 ADVANCED MEDICINAL CHEMISTRY, 3 cr odd yrs. This course will apply essential concepts of medicinal chemistry at an advanced level. Receptor theory, stereochemistry, chemical bonding, and bioisosterism will be discussed as they relate to drug design. Prereq: PHSC 626 or equivalent. Offered: Odd years. Instructor: Jonathan Vennerstrom, Ph.D.
 
843 SPECTROSCOPIC ORGANIC STRUCTURAL ANALYSIS, 3 cr even yrs. This course deals with a theoretical and practical understanding of UV, IR, NMR and MS applied to organic structural elucidation. The advantages, disadvantages, limitations, and appropriate use of each spectroscopic technique will be described. Prereq: First year organic chemistry. Offered: Varies. Instructor: Jonathan Vennerstrom, Ph.D.
 
845 QUANTITATIVE PHARMACEUTICAL ANALYSIS, 3 cr I. A lecture and laboratory course covering the theory and applications of current analytical methods for the quantitative determination of drugs, metabolites, and other biologically active agents. Lect 3, lab 3. Prereq: first year organic chemistry and permission of instructor. Offered: Even years. Instructor: Luis Marky, Ph.D.
  
848 NANOIMAGING AND BIOIMAGING, 3 cr odd yrs. This course will review various nanotechnology approaches to imaging, probing, and manipulation at the nanoscale and discuss significance and impact of these technological advances on pharmaceutical and biomedical industries. Prerequisites: Undergraduate level of Biophysical Chemistry, Permission of Instructor. Offered: Odd years. Instructor: Yuri Lyubchenko, Ph.D.

851 INNOVATIVE DRUG DELIVERY SYSTEMS, 3 cr II odd yrs. This course will examine the innovations in the design, preparation, and evaluation of modern drug delivery systems. Prereq: permission of instructor. Offered: Even years. Instructor: Dong Wang, Ph.D.

852 PHARMACEUTICAL CHEMISTRY FOR DRUG DELIVERY AND NANOMEDICINE, 3 cr even yrs. This course will review various chemical reactions and their applications in pharmaceutics, drug delivery and nanomedicine.  Practical/laboratory experiments will be included. Prereq: Polymer Therapeutics, Quantitative Pharmaceutical Sciences and Innovative Drug Delivery are recommended. Offered: Odd years. Instructor: Dong Wang, Ph.D.

861 ADVANCED PHARMACOKINETICS AND PHARMACODYNAMICS, 3 cr I even yrs. The mathematical description of the rate and extent of drug absorption, distribution, elimination and action. Prereq: PHSC 674 or permission of instructor. Offered: Varies. Instructor: TBD
 
875 CHEMICAL CARCINOGENESIS, 2 cr II even yrs. This course will present the basic concepts of chemical carcinogenesis, and introduce the major carcinogens, their biochemistry of activation and mode of action. Prereq: Biochemistry or permission of instructor. Offered: Odd years. Instructor: Eleanor Rogan, Ph.D.
 
880 PRINCIPLES AND METHODOLOGIES IN CANCER RESEARCH, 3 cr I (BIOC 880, CRGP 880, PAMM 880, PHAR 880). See BIOC 880 for course description.
 
885 PHYSICAL PHARMACY, 4 cr II odd yrs. A study of physicochemical principles applicable to drug delivery systems, with emphasis on solubility, diffusion, dispersed systems, and stability testing. Prereq: PHSC 870 or Permission of instructor. Offered: Varies. Instructor: TBD
 
890  POLYMER THERAPEUTICS, 3 cr. I even yrs.  A study of the physicochemical and biomedical properties of synthetic polymers with an emphasis on their application as modern therapeutics.  Prereq: permission of instructor. Offered: Varies. Instructor: TBD
 
896 RESEARCH OTHER THAN THESIS, 1-8 cr. Prereq: Permission of instructor. Offered: Each semester. Instructor: Advisor.
 
902 Drug Delivery and Nanomedicine Research, 3 credits. This is a webcast seminar course based on the lectures presented by outside and internal Faculty speakers in the seminar program of the Center of Drug Delivery and Nanomedicine (CDDN). Videos of these seminars are posted online. Offered: Fall semester. Instructor: Tatiana Bronich, Ph.D.

904 DELIVERY AND BIOCOMPATIBILITY OF PROTEIN AND NUCLEIC ACID DRUGS, 3 credits.  This course is designed to teach students about the delivery and biocompatibility of proteins, peptides and nucleic acid drugs and dosage form design. Topics will include: (i) biocompatibility, (iii) protein and peptide drug delivery, (iv) nucleic acid drug delivery, and (v) oligonucleotide. siRNA, shRNA, miRNA and gene therapy.

921 BIOPHYSICAL CHEMISTRY, 3 cr II even yrs. The course will cover the biophysical chemistry of nucleic acids and proteins including the study of these molecules using NMR, calorimetry, and fluorescence. Prereq: Permission of instructor. Offered: Even years. Instructor: Luis Marky, Ph.D.
 
924 DRUG METABOLISM AND DISPOSITION. 3 cr I even yrs. An in-depth consideration of the various factors which influence the metabolism of drugs and foreign chemicals (xenobiotics). Prereq: Biochemistry and permission of instructor. Offered: Varies. Instructor: TBD.
 
950 ADVANCED TOXICOLOGY, 3 cr II odd yrs. This course deals with the adverse effects of chemicals on biological systems. Physiological and biochemical mechanisms of toxicity at the cellular and subcellular levels will be emphasized. Prereq: Permission of instructor. Offered: Odd years. Instructor: JoEllyn McMillan, Ph.D.
 
960 CURRENT TOPICS IN THE PHARMACEUTICAL SCIENCES,1 cr I, II. This course is mandatory each semester for all students enrolled in the Pharmaceutical Sciences Graduate Program. Offered: Each semester. Instructor: Rotates.
 
970 SEMINAR IN PHARMACEUTICAL SCIENCES, 1 cr.  This course is mandatory for all students enrolled in the Pharmaceutical Sciences Graduate Program. Offered: Each semester. Instructor: Varies.
 
899 MASTER’S THESIS
 
999 DOCTORAL DISSERTATION

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