Dong Wang, Ph.D.

Dong Wang, Ph.D.

WangAssociate Professor
Department of Pharmaceutical Sciences
College of Pharmacy
University of Nebraska Medical Center
986025 Nebraska Medical Center
Omaha, NE 68198-6025
402-559-1995 (Office)
402-559-1323 (Lab)
402-559-9543 (Fax)
dwang@unmc.edu

Teaching Activities:
Dr. Wang lectures in Introduction to Pharmaceutical Sciences (PHSC550) and Pharmaceutical Sciences I (PHSC570) in the professional program. At graduate level, he teaches in the Quantitative Pharmaceutical Sciences (PHSC845), Physical Pharmacy (PHSC885) and Nanoimaging and Bioimaging (PHSC848). In addition, he coordinates and teaches in Innovative Drug Delivery Systems (PHSC 851) and Pharmaceutical Chemistry for Drug Delivery and Nanomedicine (PHSC 852)

Research Activities/Interests:

  1. Macromolecular therapies for inflammatory diseases.
  2. Dentrotropic therapies for oral and craniofacial diseases.
  3. Targeted therapies for musculoskeletal diseases.
  4. Click chemistry for drug delivery and nanomedicine.
  5. Biocompatible polymers for biomedical applications.
  6. Prodrug design.

Recent Publications:

    1. Chen, F.; Liu, X-M. ; Rice, K.C.; Li, X.; Yu, F.; Reinhardt, R.A.; Bayles, K.W.; Wang, D.; Tooth-binding Micelles for Dental Caries Prevention. Antimicrobial Agents and Chemotherapy, 53, pp.4898-4902. 2009

    2. Liu, X. M.; Miller, S. C.; Wang, D.; Beyond oncology - application of HPMA copolymers in non-cancerous diseases. Adv Drug Deliv Rev. 62, pp. 258-71. 2010

    3. Chen, F.; Liu, X-M.; Rice, K.C.; Reinhardt, R.A.; Bayles, K.W.; Wang, D.; Triclosan-loaded Tooth-binding Micelles for Prevention and Treatment of Dental Biofilm. Pharmaceutical Research, 2010, 27, 2356-2364.

    4. Chen, F.; Wang, D.; New Technologies for Prevention and Treatment of Dental Caries. Expert Opinion On Therapeutic Patents.,20, pp. 681-694. 2010

    5. Quan, L.D.; Purdue, P.E.; Liu, X-M, ; Boska, M.D.; Lele, S.M., Theiele, G.M.; Mikuls, T.R.; Dou, H.Y.; Goldring, S.R.; Wang, D.; Development of a Macromolecular Prodrug for the Treatment of Inflammatory Arthritis: Mechanisms Involved in Arthrotropism and Sustained Therapeutic Efficacy. Arthritis Research and Therapy.,12: R170. 2010

    6. Liu, X-M,; Wuan, L.D.; Tian, J.; Laquer, F.C.; Wang, D.; Click PEG-dexamethasone Conjugate for Effective Treatment of Rheumatoid Arthritis. Biomacromolecules., 11, pp. 2621-2628. 2010

    7. Quan, L. D.; Yuan, F.; Liu, X. M.; Huang, J. G.; Alnouti, Y.; Wang, D.; Pharmacokinetic and Biodistribution Studies of N-(2-Hydroxypropyl)methacrylamide Copolymer-Dexamethasone Conjugates in Adjuvant-Induced Arthritis Rat Model. Mol Pharm., 7, pp. 1041-1049. 2010

    8. Hein, C. D.; Liu, X. M.; Chen, F.; Cullen, D. M.; Wang, D.; The Synthesis of a Multiblock Osteotropic Polyrotaxane by Copper(I)-Catalyzed Huisgen 1,3-Dipolar Cycloaddition. Macromol Biosci., 10, pp.1544-1556. 2010

    9. Ren, K.; Purdue, P.E.; Burton, L.; Quan, L.D.; Fehringer, E.V.; Thiele, G.M.; Goldring, S.R.; Wang, D.; Early Detection of Particle-Induced INflammation and Osteolysis Using HPMA Copolymer Conjugates. Molecular Pharmaceutics. 2011, [Epub ahead of print]. (Featured on American Chemical Society April 27, 2011 News Release).

    10. Lee, Y.; Liu, X-M.; Nawshad, A.; Marx, D.B.; Wang, D.; Reinhardt, R.A.; Role of Prostaglandin Pathway and Alendronate-Based Carriers to Enhance Statin-Induced Bone. Molecular Pharmaceutics. 2011, [Epub ahead of print].