Jingwei Xie, Ph.D.

Assistant Professor

Department of Pharmaceutical Sciences
College of Pharmacy
University of Nebraska Medical Center
Durham Research Center II
Office:  Room 6031
Lab:  Rooms 6016/6017/6019
985965 Nebraska Medical Center
Omaha, NE 68198-5965
402-559-9442 (Office)
402-559-7521 (Fax)
jingwei.xie@unmc.edu

Teaching Activities:
Seminar

Research Activities/Interests:
Dr. Xie’s research interests center on the synthesis, surface modification, self-assembly of materials at nano- and/or microscale to address problems in the field of tissue engineering, regenerative medicine and drug/gene delivery. Specifically, we are interested in use of nano-structured materials together with signaling molecules to regulate cell/stem cell behaviors for regenerating various types of tissues including tendon-to-bone insertion site, cartilage, bone, skin, cardiac muscle, and nerve. We are also interested in developing nanofibrous materials as local drug delivery devices for prevention of surgical site infection.

Recent Publications:

  1. Xie J, Liu W, MacEwan MR, Bridgman PC, Xia Y (2014) “Neurite outgrowth on electrospun nanofibers with uniaxial alignment: the effects of fiber density, surface coating, and supporting substrate.” ACS Nano DOI: 10.1021/nn406363j.
  2. Jiang J, Xie J, Ma B, Bartlett DE, Wang CH (2014) “A mussel-inspired coating finely tailoring pH-responsive drug delivery from electrospun nanofibers.” Acta Biomaterialia 10: 1324-1332.
  3. Ma B, Xie J, Jiang J, and Wu J (2014) “Sandwich-type fiber scaffolds with square arrayed microwells and nanostructured cues as microskin grafts for skin regeneration.” Biomaterials 35, 630-641.
  4. Ma B, Xie J, Jiang J, Shuler FD, Bartlett DE (2013) “Rational design of nanofiber scaffolds for orthopaedic tissue repair and regeneration.” Nanomedicine 8: 1459-1481.
  5. Xie J, Zhong S, Ma B, Shuler FD, Lim CT (2013) “Controlled biomineralization of electrospun poly(ε-caprolactone) fibers for enhancing their mechanical properties.” Acta Biomaterialia 9: 5698-5707.
  6. Xie J, Ma B, Michael PL (2012) “Fabrication of novel 3D nanofiber scaffolds with anisotropic property and regular pores and their potential applications.”  Advanced Healthcare Materials 1: 674-678.
  7. Xie J, Michael PL, Zhong S, Ma B, MacEwan MR, Lim CT (2012) “Mussel inspired protein-mediated surface modification to electrospun fibers and their potential biomedical applications.” Journal of Biomedical Materials Research Part A, 100A: 929-938.
  8. Xie J, Liu W, MacEwan MR, Yeh YC, Thomopoulos S and Xia Y (2011) “Nanofiber membranes with controllable microwells and structural cues and their use in forming cell microarrays and neuronal networks.” Small 7: 293-297.
  9. Xie J, MacEwan MR, Ray WZ, Liu W, Siewe DY and Xia Y (2010) “Radially aligned, electrospun nanofibers as dural substitutes for wound closure and tissue regeneration applications.”ACS Nano 4: 5027-5036.
  10. Xie J, Willerth SM, Li X, Macewan MR, Rader A, Sakiyama-Elbert SE and Xia Y (2009) “The differentiation of embryonic stem cells seeded on electrospun nanofibers into neural lineages.” Biomaterials, 30: 354-362.

Jingwei Xie, Ph.D.
Dr. Xie
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