Current Grant Projects

Dr. Carmines

Tyrosine Kinases in Renal Vasoconstrictor Signaling
National Institutes of Health

Tyrosine Kinases in Renal Vasoconstrictor Signaling
Administrative Supplement 
National Institutes of Health

Mitochondrial Redox Systems in Neurogenic Hypertension
(Co-Investigator)
Nation Institutes of Health

$193,123


$66,519

Neuro-Circulatory Function in Chronic Heart Failure
Core B, Animal Core
National Institutes of Health

Short Course: Integrative and Organ Systems Pharmacology
(Co-Investigator)
National Institutes of Health

Hirschmann Prize for Teaching Excellence
College of Medicine – University of Nebraska Medical Center

$156,062







$13,000

Regulation of Apoptosis in Renal Ischemia
National Institute of Health

Mechanism of Glycolytic Inhibition in Ischemic Kidneys
American Heart Association

Role of PARP-1 in Childhood and Adolescent Obesity
Edna Trust Fund UN Foundation

Dean’s Indirect Cost Program: Neural Regulation of Kidney Remodeling
IN Chronic Heart Disease.

Unemed Corporation Best New Invention

Short Course: Integrative and Organ Systems Pharmacology
(Co-Investigator)
National Institutes of Health

$205,425


$65,000

$38,753

$30,000

$10,000

Neuro-Circulatory Function in Chronic Heart Failure
Project II: The Role of Excitatory Input into the PVN on Increased Sympathetic
Drive in Heart Failure Function (PI)
Project I: Regulation of Central AT1R Expression in Heart Failure and Modulation
by Exercise Training (Co-Investigator)
National Institutes of Health

Altered CNS Intercellular Signaling Mechanisms
in Cardiovascular Disease
National Institutes of Health

Exercise Training Improves Erectile Dysfunction
in Diabetes: Role of Central Mechanisms
National Institutes of Health

Deans Indirect Cost Program: The Role of the Renal Nerves on ENAC
Expression and Function in CHF.

$282,561






$44, 193



$213,172



$30,000

Redox Biology Center
Subcontract with University of Nebraska – Lincoln
National Institutes of Health

Mitochondrial Dysfunction, Oxidative Damage & Inflammation in Claudication
National Institutes of Health (Co-Investigator)

$7,599

Dr. Sansom

Role of BK-Beta 1 in flow dependent K+ Secretion in the CNT
National Institutes of Health

Role of BK-Beta 1 in flow dependent K+ Secretion in the CNT
National Institutes of Health

*Role of BK-alpha/beta 4 in Renal Secretion
National Institutes of Health

Neuro-Circulatory Function in Chronic Heart Failure
Project III: Chemoreflex Function in Heart Failure (PI)
Project I: Regulation of Central AT1R Expression in Heart Failure and Modulation
by Exercise Training (Co-Investigator)
National Institutes of Health

*Therapeutic Efficacy of Carotid Body Denervation in Progression of Heart
Failure
Coridea NC1, Inc.

*Pharmacologic Modulation of Peripheral Chemosensitivity and Ventilation
In a Rat Heart Failure Model
Sova Pharmaceuticals, Inc.

Mitochondrial Redox Systems in Neurogenic Hypertension
National Institutes of Health (Co-Investigator)

$275,200

$90,000

$11,499

*The Cardiac Sympathetic Afferent Reflex in Heart Failure:
Role of the RVLM
American Heart Association

$65,000

Enhanced Sympathoexcitation in Diabetes: Roles
of Hyperglycemia Angiotensin II, Oxidative-Nitrosative Stress
American Heart Association

Neuro-Circulatory Function in Chronic Heart Failure
Project II: The Role of Excitatory Input into the PVN on Increased
Sympathetic Drive in Heart Failure Function (Co-Investigator)
National Institutes of Health

Exercise Training Improves Erectile Dysfunction
in Diabetes: Role of Central Mechanisms (Co-Investigator)
National Institutes of Health

Electron Paramagnetic Resonance (EPR) Spectroscopy Facility
Subcontract with University of Nebraska-Lincoln

Mitochondrial Redox Systems in Neurogenic Hypertension
National Institutes of Health

Nebraska Center for Nanomedicine – Seed Project
National Institutes of Health

Nebraska Center for Nanomedicine – Project 2
National Institutes of Health

Role of Superoxide vs. Hydrogen Peroxide in the
Redox Regulation of Angiotensin II-Induced Synpathoexcitation
American Heart Association

Neuro-Circulatory Function in Chronic Heart Failure
The Molecular Biology, Biochemistry & Histology Core (Co-investigator)
National Institutes of Health

$ 10,000


$250,000

$50,000

$125,000

$70,000

Sympathetic Control in Heart Failure: A Role for Statins
National Institutes of Health

Neuro-Circulatory Function in Chronic Heart Failure
Project I: Regulation of Central AT1R Expression in Heart Failure and
Modulation by Exercise Training
Core A: Administration Core
Core C: Molecular Biology, Biochemistry and Histology (Co-Director)
National Institutes of Health

Oxidative Stress Causes Chronic Orthostatic Intolerance
New York Medical

Dean’s Indirect Cost Program: The Role of the Renal Nerves in AT1R
Express in CHF.

$294,523



$270,876
$119,791
$128,781



$19,474

$30,000

 
Karla Haack

Neuro-Circulation in Chronic Heart Failure
Postdoctoral Research Supplement
National Institutes of Health
Sponsor: Dr. Irving Zucker

$51,000

*Brain Delivery of Nanformultaed Superoxide Dismutase
National Institutes of Health
Sponsor: Dr. Matthew Zimmerman

 
Ryan Cornelius

*Role of Intercalated Cell BK Alpha-beta 4 in Potassium Secretion
American Heart Association
Sponsor: Dr. Steven Samson

$26,000