Huanqing Li
Curriculum Vitae

Ph.D. 2006, Chinese Academy of Sciences
Specialty: Physical electronics
Major Interest: Biosensor, Instrumentation, Signal Sampling and Processing

Maintaining a right concentration range in plasma is very important for the proper functioning of our heart, muscles and nerves. Research in the laboratory is focused on fully understanding the mechanisms behind how the kidneys regulate K balance when there is a high K dietary intake or an unexpected elevation. Our laboratory has identified two types of potassium channels (BK-α/β1 and BK-α/β4) that are able to handle a high K diet. While using traditional in-vitro tools such as AAS, HPLC, patch-clamp, and in-vivo micro-puncture technique to determine the role of the potassium channels during Na-independent K excretion, we are attempting to develop novel analytical technology such as biosensors and tubule-on-a-chip. The development of the biosensor would enable long-term, real-time monitoring of a range of variables that are relevant to function of the potassium channels. My main focus is to study the state-of-the-art technologies to advance the biosensing technique, providing powerful tools for physiologists to study the kidney function in-vivo/vitro. My research endeavors on biosensor development will span many disciplines including analytical chemistry, nanotechnology, surface chemistry, material science, biotechnology, device physicals, and electrical engineering.

Biosensor Development

Recent publications:

  1. Li, H., Martha, S. K., Unocic, R. R., Luo, H., Dai, S., and Qu, J. High Cyclability of Ionic Liquid-Produced TiO2 Nanotube Arrays as an Anode Material for Lithium-Ion Batteries, Journal of Power Sources 218,88–92. 2012.
  2. Li, H., Lopes, N., Moser, S., Sayler, G., and Ripp, S. Silicon photomultiplier (SPM) detection of low-level bioluminescence for the development of deployable whole-cell biosensors: Possibilities and limitations, Biosensors and Bioelectronics 33, 299-303. 2012. PMID 22305444
  3. Li, H., Qu, J., Cui, Q., Xu, H., Luo, H., Chi, M., Meisner, R. A., Wang, W., and Dai, S. TiO2 nanotube arrays grown in ionic liquids: high-efficiency in photocatalysis and pore-widening, J. Mater. Chem. 21, 9487-9490. 2011.
  4. Li, H., and Wu, N. A large-area nanoscale gold hemisphere pattern as a nanoelectrode array, Nanotechnology 19, 275301. 2008. PMID 21828697
  5. Li, H., Low, J., Brown, K. S., and Wu, N. Large-area well-ordered nanodot array pattern fabricated with self-assembled nanosphere template, Sensors Journal, IEEE 8, 880-884. 2008.