Harold D. Schultz

Harold D. Schultz
Curriculum Vitae

Ph.D. 1979, University of Illinois
Specialty: Neurophysiology
Major Interest: Sensory and motor functions of the autonomic nervous system

Our laboratory is devoted to the study of chemoreflex and baroreflex regulation of cardio-respiratory function in health and exercise and how these reflexes are altered in diseases such as heart failure. Much of our effort is devoted to exploring the cellular and molecular mechanisms of sensory transduction in cardiovascular chemoreceptor and baroreceptor nerves. In particular, we are interested in the characteristics of certain types of mechano- and chemo-sensitive channels identified in these sensory neurons. Members of our lab carry out neurophysiological experiments using a variety of techniques.
Figure A

Recent publications:

  1. Schultz, HD and Marcus, NJ. Heart failure and carotid body chemoreception. Adv Exp Med Biol. 2012;758:387-95. PMID: 23080187.
  2. Marcus, NJ, Philippi, NR, Bird, CE, Li, YL, Schultz, HD and Morgan, BJ. Effect of AT1 receptor blockade on intermittent hypoxia-induced endothelial dysfunction. Respir Physiol Neurobiol. 2012;183(2):67-74. PMID: 22728949
  3. Zucker, IH, Patel, KP and Schultz, HD. Neurohumoral stimulation. Heart Fail Clin. 2012;8(1):87-99. PMID: 22108729
  4. Schlenker, EH and Schultz, HD. Hypothyroidism stimulates D2 receptor-mediated breathing in response to acute hypoxia and alters D2 receptors levels in carotid bodies and brain. Respir Physiol Neurobiol. 2012;180(1):69-78. PMID: 22051191
  5. Patel, KP and Schultz, HD. Angiotensin Peptides and Nitric Oxide in Cardiovascular Disease. Antioxid Redox Signal. 2012. PMID: 22462736.
  6. Schultz, HD, Del Rio, R, Ding, Y and Marcus, NJ. Role of neurotransmitter gases in the control of the carotid body in heart failure. Respir Physiol Neurobiol. 2012;184(2):197-203. PMID: 22842006; PMCID: 3483421.